Outcome of Women With Cervical Cancer

NCT ID: NCT02026648

Last Updated: 2016-09-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

81 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-01-31

Study Completion Date

2016-05-31

Brief Summary

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Squamous cell carcinoma (SCC) of the cervix has showed a marked decline in developed countries over the past 40 years, however, there has also been an increase in relative and absolute incidence of adenocarcinoma and adenosquamous carcinoma (AC) of the uterine cervix over the same period.

Our understanding of the natural history and optimal management of AC is limited. It appears that AC and SCC of the cervix behave differently. They are different in epidemiology, prognostic factors, and patterns of failure after similar treatments. Available data suggest that they may also differ in their response to treatment. We postulate that new treatment strategies specifically tailored to AC should be explored.

However, there is few data about outcome of cervical cancer in Taiwan. So we propose this proposal for retrospective analysis of clinicopathological parameters and outcomes in patients of cervical cancer, especially for cervical adenocarcinoma and adenosquamous carcinoma.

Detailed Description

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Conditions

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Cervical Cancer

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

RETROSPECTIVE

Study Groups

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cases with cervical cancer

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Time interval: from 1991 to date.
* Comprehensive surgical staging, debulking procedure, radiotherapy or chemotherapy.
* All female patients with cervical cancer who underwent treatment for cervical cancer at Far Eastern Memorial Hospital.
* All the patients diagnosed as cervical cancer, especially for women with adeno- and adenosquamous carcinoma.
* To review:

1. Clinical data: including age at diagnosis, presenting symptoms, gravidity, parity, menstrual history, body mass index, history of diabetes, hypertension, personal history of cancer and staging.
2. Pathologic information: deep stromal invasion, lymph-vascular space invasion, lymph node involvement, parametrium invasion, vaginal cut end and tumor size.
3. Survival data: disease-free and overall survival.
4. Radiation report, Chemotherapy treatment, operation, discharge and admission note.

Exclusion Criteria

* Not comprehensive staging/debulking procedure.
* Patients who died of postoperative complications within 30 days after surgery were excluded from the survival analysis.
* Female minors or disabled persons.
Minimum Eligible Age

20 Years

Maximum Eligible Age

99 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Far Eastern Memorial Hospital

OTHER

Sponsor Role lead

Responsible Party

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Sheng-Mou Hsiao

Chief, Department of Obstetrics & Gynecology

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Far Eastern Memorial Hospital

Banqiao District, Taipei, Taiwan

Site Status

Countries

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Taiwan

Other Identifiers

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102159-E

Identifier Type: -

Identifier Source: org_study_id

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