Cold Magnesium Sulfate Solution for Perineal Swelling Following Vaginal Delivery

NCT ID: NCT02024256

Last Updated: 2016-09-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

206 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-01-31

Brief Summary

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The purpose of this study is to compare the impact of treatment with cooled magnesium sulfate and cold water-soaked pads on perineal pain and swelling following vaginal delivery.

Assessment of appropriateness for each patient to take part in the study will be performed approximately 2 hours following delivery. Those patients who consent to participate in the trial will be allocated to treatment groups in a double-blinded, randomized manner. Women in the study group will receive treatment with pads soaked in a cold aqueous solution of magnesium sulfate at 33% (w/v) concentration, while those in the control group will receive treatment with pads soaked in cold water.

Nurses will initiate treatment according to the group to which the patient was randomized. Said pads will be given the patients routinely 5 times a day at regular times.

A physician will assess the perineal swelling according to visual (photographed) scale in which severe, moderate, light and no swelling will be defined. Measurement of swelling in centimeters (maximal length and breadth); photography, by a medical photographer or the examining doctor, of the perineal area with a centimeter ruler, before, during and after treatment (photography is dependent on patient approval and is not a precondition to participation in the trial.); and additional examination, on the above basis, will be performed regarding hemorrhoids in the event that a patient has complained of such.

A nurse will assess the perineal pain and swelling on a scale ranging from 0 to 10 prior to the patient being given the pad and an hour following treatment. An additional assessment by the same method will be performed regarding hemorrhoid pain. Any analgesia administered will also be recorded.

Likewise, for follow-up purposes a blood test for serum magnesium concentration will be taken before and after treatment.

Period of follow-up will be 48-72 hours from childbirth.

Detailed Description

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Conditions

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Vaginal Delivery Perineal Swelling Perineal Pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Caregivers Investigators

Study Groups

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Magnesium sulfate

Pads soaked in cold magnesium sulfate solution

Group Type ACTIVE_COMPARATOR

Cold pads soaked in Magnesium sulfate solution

Intervention Type OTHER

Water

Pads soaked with cold water

Group Type SHAM_COMPARATOR

Cold pads soaked in water

Intervention Type OTHER

Interventions

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Cold pads soaked in Magnesium sulfate solution

Intervention Type OTHER

Cold pads soaked in water

Intervention Type OTHER

Other Intervention Names

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Epson salt, MgSo4

Eligibility Criteria

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Inclusion Criteria

* parturients following normal vaginal birth or vacuum-assisted vaginal delivery
* reporting of perineal pain equal to or greater than 3 on a 0-10 scale

Exclusion Criteria

* parturients following cesarean section
* lack of consent to take part in the study
* parturients interested in early discharge (within 48 hours of childbirth)
* girls under 18 years of age
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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HaEmek Medical Center, Israel

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Zohar Nahum, MD

Role: PRINCIPAL_INVESTIGATOR

HaEmek medical center affiliated to Rappaport faculty of medicine, Technion, Haifa, Israel

Locations

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HeEmek medical center

Afula, , Israel

Site Status RECRUITING

HaEmek medical center

Afula, , Israel

Site Status RECRUITING

Countries

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Israel

Central Contacts

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Zohar Nahum, MD

Role: CONTACT

97246494158

Irit Friedman, MA

Role: CONTACT

Facility Contacts

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Zohar Nahum, md

Role: primary

97241584649

Irit Friedman

Role: backup

References

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East CE, Dorward ED, Whale RE, Liu J. Local cooling for relieving pain from perineal trauma sustained during childbirth. Cochrane Database Syst Rev. 2020 Oct 9;10(10):CD006304. doi: 10.1002/14651858.CD006304.pub4.

Reference Type DERIVED
PMID: 33034900 (View on PubMed)

Other Identifiers

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MG33

Identifier Type: -

Identifier Source: org_study_id

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