Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
100 participants
OBSERVATIONAL
2014-02-28
2014-12-31
Brief Summary
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Detailed Description
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* Race, gender, age
* Height and weight
* Perceived stress level (potentially measured using Cohen's Perceived Stress scale(PSS))
* Activity level, with description hours per week, cardio versus non-cardio, and intensity (mild, moderate, intense)
* Smoking history, alcohol consumption, caffeine intake, and drug use (recreational, medicine - over - the - counter and prescription, including birth control pills)
* Hand dominance, and leg dominance
* Past medical history - with emphasis on cardiovascular disease (hypertension, cancer, coronary heart disease, diabetes mellitus, high cholesterol, coagulopathies, previous thromboses) as well as renal, adrenal, and thyroid disorders, Raynaud's phenomenon
* Family medical history (cancer, coronary heart disease, diabetes mellitus, high cholesterol)
Participants with known existing diabetes, coronary artery disease, or a history of vascular disease will be included in the study; nevertheless, their results may be analyzed in a separate cohort for comparison against those undiagnosed with the aforementioned condition.
The TBI (Toe - Brachial Index) will be measured by the following procedure.
* The assessment time and room temperature will be recorded
* The participant should lay supine for a minimum of five minutes in a warm and comfortable room
* Select the appropriate cuff for each upper arm and each large toe and separately placed them around the arm and large toe.
* The blood pressure measurements will be performed with photo plethysmography (PPS) and chart recorder. The phototransducer is connected to the PPS, and the digit cuff is connected to an aneroid sphygmomanometer.
* The toe and ipsilateral arm systolic blood pressures will be measured up to three times for accuracy.
* The TBI will be calculated by dividing the averaged toe systolic blood pressure, by the averaged brachial systolic blood pressure.
The ABI (Ankle - Brachial Index) will be measured by the following procedure.
* The blood pressure cuff will be placed proximal to the malleoli and ultrasound gel cover the skin overlying the dorsalis pedis and posterior tibial arteries in the foot.
* The dorsalis pedis and posterior tibial arteries blood pressure will be measured by using hand-held Doppler probe.
* The ankle systolic blood pressure will be taken as the higher pressure of the 2 arteries at the ankle.
* The ABI will be calculated by dividing the ankle systolic blood pressure, by the averaged brachial systolic blood pressure.
The brachial, toe and ankle blood pressures will be measured on the opposite limbs, and the TBI and ABI will be calculated following the protocol outlined above.
Conditions
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Study Design
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CASE_ONLY
CROSS_SECTIONAL
Study Groups
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Toe-Brachial and Ankle-Brachial Index
toe systolic blood pressure, ankle systolic blood pressure, brachial systolic blood pressure test
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
20 Years
35 Years
ALL
Yes
Sponsors
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University of British Columbia
OTHER
Responsible Party
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Principal Investigators
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York N Hsiang, MB FRCSC
Role: PRINCIPAL_INVESTIGATOR
UBC, Division of Vascular Surgery and Vancouver General Hospital
Locations
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Vancouver General Hospital (VGH) - Gordon and Leslie Diamond Health Care Centre
Vancouver, British Columbia, Canada
Countries
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Central Contacts
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Facility Contacts
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References
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Quong WL, Fung AT, Yu RY, Hsiang YN. Reassessing the normal toe-brachial index in young healthy adults. J Vasc Surg. 2016 Mar;63(3):652-6. doi: 10.1016/j.jvs.2015.09.019.
Other Identifiers
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H13-03144
Identifier Type: -
Identifier Source: org_study_id
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