French Digestive Polyposis Cohorte Family Adenomatous Polyposis With APC and MYH Gene Mutations , Cowden's Disease With PTEN Gene Mutation, Peutz Jeghers Disease With STK 11 Gene Mutation ,juvénil Polyposis With SMAD 4 Gene Mutation , Serrated and Hyperplastic Polyposis

NCT ID: NCT01987518

Last Updated: 2018-02-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

350 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-01-31

Study Completion Date

2020-08-31

Brief Summary

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French cohorte about polyposis digestive diseases

Detailed Description

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Family Adenomatous Polyposis APC and MYH Genes Peutz Jeghers Disease Cowden Disease Festooned polyposis Juvenile polyposis Hyperplastic polyposis

Conditions

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Quality of Life

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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digestive polyposis

Family adenomatous polyposis (APC or MYH genes) Peutz Jeghers Disease Cowden Disease Festooned Polyposis Juvenile Polyposis Hyperplastic Polyposis

Procedure surgery behavioral and genetic diagnosis

Intervention Type OTHER

Observational Study

quality of life after different type of surgery

Intervention Type PROCEDURE

Interventions

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Procedure surgery behavioral and genetic diagnosis

Observational Study

Intervention Type OTHER

quality of life after different type of surgery

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* APC Gene mutation
* MYH Homozygote mutation
* COWDEN Disease with PTEN gene mutation
* Peutz Jeghers Disease with STK 11 gene mutation
* Juvenile polyposis with SMAD 4 gene mutation

Exclusion Criteria

* heterozygote MYH Gene Mutation
Minimum Eligible Age

12 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hôpital Edouard Herriot

OTHER

Sponsor Role lead

Responsible Party

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Jean Christophe Saurin

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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jean christophe saurin, msd

Role: PRINCIPAL_INVESTIGATOR

HEH Hospital

Locations

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Hopital Edouard Herriot

Lyon, Auvergne-Rhône-Alpes, France

Site Status RECRUITING

Countries

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France

Facility Contacts

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Saurin Jean Christophe, msd

Role: primary

(33)0472117572

Vinet Olivier, CRA

Role: backup

(33)0472110370

Other Identifiers

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SISRA

Identifier Type: OTHER

Identifier Source: secondary_id

Peps Data Base

Identifier Type: -

Identifier Source: org_study_id

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