Antro-pyloro-duodenal Motility in Idiopathic Gastroparesis

NCT ID: NCT01519180

Last Updated: 2014-09-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

32 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-01-31

Study Completion Date

2014-01-31

Brief Summary

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Impaired gastric emptying may cause dyspeptic symptoms including nausea, vomiting and even nutritionnal impairment. Delay in gastric emptying may result from antro-pyloro-duodenal motility impairement.

Detailed Description

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The aim of this study is therefore to measure antro-pyloro-duodenal motor activity in patients with idiopathic gastroparesis.

Conditions

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Gastroparesis

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Control group

Healthy volunteers

No interventions assigned to this group

Idiopathic gastroparesis

Idiopathic gastroparesis

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Idiopathic gastroparesis or healthy volunteers
* Idiopathic gastroparesis must have delayed gastric emptying shown using C13 breath test

Exclusion Criteria

* Diabetic or post-surgical gastroparesis
* Treatment modifying GI motility (prokinetics, opioids...)
* Parkinson or neurologic disease
* Evoluting inflammatory process or neoplasia
* Treatment modifying coagulation
* Patients not affiliated to the French healthcare insurance
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University Hospital, Rouen

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Guillaume Gourcerol, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

University Hospital, Rouen

Locations

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Service de Physiologie

Rouen, Haute Normandie, France

Site Status

Countries

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France

References

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Soliman H, Wuestenberghs F, Desprez C, Leroi AM, Melchior C, Gourcerol G. Physiological characterization of gastric emptying using high-resolution antropyloroduodenal manometry. Am J Physiol Gastrointest Liver Physiol. 2024 Jan 1;326(1):G16-G24. doi: 10.1152/ajpgi.00101.2023. Epub 2023 Oct 24.

Reference Type DERIVED
PMID: 37874655 (View on PubMed)

Other Identifiers

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2010/148/HP

Identifier Type: -

Identifier Source: org_study_id

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