Safety of Hib Vaccine (Bio Farma)

NCT ID: NCT01977170

Last Updated: 2013-11-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE1

Total Enrollment

25 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-11-30

Study Completion Date

2010-12-31

Brief Summary

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The objective of this study was to know the safety of Hib/PRP-T vaccine and immediate reactions within the first 30 minutes after injection.

Detailed Description

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This trial was an open-label study, no randomization, and no placebo or control group. Total 25 young healthy adult (volunteers) followed this trial. The safety was assessed within 24 hours, 48 hours, 72 hours, and 28 days after injection.

Conditions

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Healthy

Keywords

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Adults Hib vaccines Immunogenicity Safety

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Hib/PRP-T vaccine

One dose, correspond to 0.5 ml, composed of:

PRP-T 10ug NaCl 0.85%

Frequency: 1 injection

Group Type EXPERIMENTAL

Hib/PRP-T vaccine

Intervention Type BIOLOGICAL

Hib liquid vaccine

Interventions

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Hib/PRP-T vaccine

Hib liquid vaccine

Intervention Type BIOLOGICAL

Eligibility Criteria

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Inclusion Criteria

* Adult (age 18 - 40 years old)
* Provision of written informed consent
* Good health according to the clinical investigator
* Willingness and ability to adhere to the regimen of the study

Exclusion Criteria

* Known not enrolled in other study
* Pregnancy or lactation
* Known or suspected allergy to any of the vaccine component (by medical history)
* History of unusual reaction to any previous vaccination
* Known or suspected immune deficiency, or use of medication that may influence the immune system
* Prior respiratory infection
* Other vaccination during the study, or one week before (inactivated vaccine) or one month (live vaccine) before the study
* Acute febrile illness (temperature \> 37.5 Celsius)
* Present evidence of serious diseases demanding medical treatment
* Any significant congenital or chronic disorder
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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PT Bio Farma

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Kusnandi Rusmil, PhD

Role: PRINCIPAL_INVESTIGATOR

Faculty of Medicine UNPAD

Locations

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Hasan Sadikin Hospital

Bandung, West Java, Indonesia

Site Status

Countries

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Indonesia

Other Identifiers

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Hib 0110

Identifier Type: -

Identifier Source: org_study_id