Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
40 participants
INTERVENTIONAL
2013-09-30
2015-07-31
Brief Summary
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Detailed Description
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Age: between 18 years mechanical ventilation RASS≥2 A diagnosis of sepsis within 48 hours
Exclusion Criteria:
Cardiac disease Cardiac rhythm abnormalities liver dysfunction coma severe hypotension muscle relaxant users
Primary Outcome Measures:
Dose of dexmedetomidine
Secondary Outcome Measures:
RASS score Requirement for rescue intervention, RASS will be recorded per hour.
Conditions
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Study Design
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RANDOMIZED
SINGLE_GROUP
SUPPORTIVE_CARE
DOUBLE
Study Groups
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dexmedetomidine,sepsis,ED50
Intervention Name: dexmedetomidine dosage form: intravenous injection dosage：0.2-0.7μg/kg/h frequency: 1 duration:12 hours
Dexmedetomidine
Septic patients are randomly received 1 of 6 doses( 0.2,0.3,0.4,0.5,0.6,0.7μg/kg/h) dexmedetomidine.
Interventions
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Dexmedetomidine
Septic patients are randomly received 1 of 6 doses( 0.2,0.3,0.4,0.5,0.6,0.7μg/kg/h) dexmedetomidine.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
18 Years
65 Years
ALL
No
Sponsors
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First Affiliated Hospital of Zhejiang University
OTHER
Responsible Party
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zhanqin zhang
PHD candidate
Principal Investigators
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xiangming fang, PHD
Role: PRINCIPAL_INVESTIGATOR
First Affiliated Hospital of Zhejiang University
Locations
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Zhanqin Zhang
Hangzhou, Zhejiang, China
Countries
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Other Identifiers
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FirstzhejiangU
Identifier Type: -
Identifier Source: org_study_id
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