Observational Study Providing 12 Months of Safety Follow-Up From First Exposure to HP802-247

NCT ID: NCT01970657

Last Updated: 2017-06-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

221 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-05-31

Study Completion Date

2015-11-30

Brief Summary

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This observational safety follow-up study enrolled subjects from the 802-247-09-032 study with the investigational product HP802-247 for venous leg ulcers, who received at least one application of HP802-247 or Vehicle (Placebo). This study is being done for the following purposes:

1. to identify new adverse events,
2. to examine ongoing adverse events not resolved in subjects who participated in the 802-247-09-032 trial,
3. to record wound status, and
4. to determine if there are differences in Health Related Quality of Life (HRQoL) associated with the treatment assignment from the 802-247-09-032 Trial.

About 440 subjects were to participate depending upon subject enrollment from the previous study, 802-247-09-032. The study was conducted in approximately 50 sites in Europe.

Detailed Description

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Subjects transitioned to this observational study immediately upon exit from the 802-247-09-032 trial. This ensured a total of 12 months of safety observations and wound status data were obtained from the time of the first application of HP802-247. This study provided consecutive visits at intervals of 8 weeks until a total of 12 months of safety follow-up had been achieved, based on the initial application of Investigational Medicinal Product in the prior study. Specifically, this study examines all new and unresolved ongoing adverse events.

Conditions

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Venous Leg Ulcer (VLU)

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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HP802-247 in prior study

Observational safety follow up study, no treatment specified

No treatment specified

Intervention Type BIOLOGICAL

No intervention

Vehicle Control in prior study

Observational safety follow up study, no treatment specified

No treatment

Intervention Type BIOLOGICAL

None specified

Interventions

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No treatment specified

No intervention

Intervention Type BIOLOGICAL

No treatment

None specified

Intervention Type BIOLOGICAL

Eligibility Criteria

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Inclusion Criteria

* The informed consent document must be read, signed, and dated by the subject or the subject's legally authorized representative before conducting any study procedures or exams.
* Subject was randomized in 802-247-09-032 and received at least one application of test article.
* Subject has ended their participation in 802-247-09-032 by virtue of completing the study, or by dropping out prior to completion.

Exclusion Criteria

* Subjects who refuse to provide written informed consent for this study will be excluded from this study.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Healthpoint

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Wolfgang Vanscheidt, MD

Role: PRINCIPAL_INVESTIGATOR

University Freiburg-Practice for Dermatology

Locations

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Brussels, , Belgium

Site Status

Edegem, , Belgium

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Ghent, , Belgium

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Brno, , Czechia

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Hradec Králové, , Czechia

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Olomouc, , Czechia

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Pardubice, , Czechia

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Plzen-Bory, , Czechia

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Prague, , Czechia

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Třebíč, , Czechia

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Uherské Hradiště, , Czechia

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Ústí nad Labem, , Czechia

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Bochum, , Germany

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Bonn, , Germany

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Cologne, , Germany

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Dresden, , Germany

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Düsseldorf, , Germany

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Essen, , Germany

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Freiburg im Breisgau, , Germany

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Göttingen, , Germany

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Greifswald, , Germany

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Hamburg, , Germany

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Kiel, , Germany

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Krefeld, , Germany

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Magdeburg, , Germany

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München, , Germany

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Münster, , Germany

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Budapest, , Hungary

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Debrecen, , Hungary

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Hatvan, , Hungary

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Orosháza, , Hungary

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Sátoraljaújhely, , Hungary

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Szeged, , Hungary

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Szolnok, , Hungary

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Krakow, , Poland

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Lodz, , Poland

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Lublin, , Poland

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Poznan, , Poland

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Rzeszów, , Poland

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Studzionka, , Poland

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Warsaw, , Poland

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Wroclaw, , Poland

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Zabrze, , Poland

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Countries

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Belgium Czechia Germany Hungary Poland

Other Identifiers

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802-247-09-033

Identifier Type: -

Identifier Source: org_study_id

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