Efficacy and Safety of Raltitrexed-based Transarterial Chemoembolisation(TACE)for Colorectal Cancer Liver Metastases
NCT ID: NCT01959061
Last Updated: 2017-03-13
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
PHASE4
320 participants
INTERVENTIONAL
2013-09-30
2017-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
TREATMENT
NONE
Study Groups
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Raltitrexed and Oxaliplatin
Raltitrexed and Oxaliplatin were mixed with 10-15 ml lipiodol by arterial chemoembolization on day 1 and during each 28-day cycle.
Raltitrexed
4mg, every 4 weeks,transhepatic arterial infusion
Oxaliplatin
100\~150mg, every 4 weeks, transhepatic arterial infusion
lipiodol
5-20ml, every 4 weeks, hepatic artery embolization
Interventions
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Raltitrexed
4mg, every 4 weeks,transhepatic arterial infusion
Oxaliplatin
100\~150mg, every 4 weeks, transhepatic arterial infusion
lipiodol
5-20ml, every 4 weeks, hepatic artery embolization
Eligibility Criteria
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Inclusion Criteria
2. Disease limited to the liver Unresectable disease by surgery or other local therapies
3. Age \>18 years
4. ECOG performance status 0-2,Child pugh A or B
5. Expected survival ≥ 3 months
6. Adequate hematological, hepatic, and renal function
Exclusion Criteria
2. Patients with severe organ dysfunction or failure
3. With severe cardiovascular disease, or mental
4. Extraliver metastases
18 Years
75 Years
ALL
No
Sponsors
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Nanjing Chia-tai Tianqing Pharmaceutical
INDUSTRY
Responsible Party
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Principal Investigators
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Jianhua Wang
Role: PRINCIPAL_INVESTIGATOR
Fudan University
Locations
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Zhongshan Hospital Fudan University
Shanghai, Shanghai Municipality, China
Countries
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Central Contacts
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Facility Contacts
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Jianhua Wang
Role: primary
Other Identifiers
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NJCTTQ-01
Identifier Type: -
Identifier Source: org_study_id
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