Causative Diagnosis on Prosthetic Joint Infections: Establishment of a Comprehensive Diagnostic Strategy

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

980 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-10-07

Study Completion Date

2022-10-26

Brief Summary

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On joint orthopaedic hardware infections are one of the most frequently encountered complications in orthopaedic surgery. However 6% of the cultures remain sterile, etiological diagnosis cannot be established despite obvious signs of infection. As part of this research project, we have developed a new strategy diagnosis including directly the use of PCR to reduce the number of negative results. This should have a major therapeutic impact in terms of timeliness and specificity of antibiotic.

Primary:

Evaluate the effectiveness of the new diagnostic strategy on etiological identification of prosthesis infections.

Hypothesis:

Minimum 6 percent increase in the number of patients with an etiological diagnosis of infection on prosthesis.

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Detailed Description

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Conditions

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Prosthetic Joint Infections

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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bone biopsies

Group Type EXPERIMENTAL

bone biopsies

Intervention Type PROCEDURE

Interventions

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bone biopsies

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patient is more than 18 years old.
* Patient with a prescription of a microbiologic diagnostic of Prosthetic joint infection
* Patient who do not declined to have his medical records reviewed for research
* Patient with health insurance