Calmodulin Gene Mutations in Patients With Ventricular Arrhythmia of Unknown Origin - A Screening Study

NCT ID: NCT01947543

Last Updated: 2018-04-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Study Classification

OBSERVATIONAL

Study Start Date

2017-01-31

Study Completion Date

2018-04-30

Brief Summary

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The aim of this study is to screen a well characterized patient population with ventricular tachycardia of unknown origin and treated with an implantable cardioverter-defibrillator (ICD) for mutations in the calmodulin genes.

Detailed Description

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Patients with ventricular tachycardia of unknown origin and treated with an implantable cardioverter-defibrillator (ICD) will be asked to participate in the study. For patients with results showing mutations in the calmodulin genes, family members (parents, siblings and children) will also be asked to participate in the study. For under age patients and relatives who agree to participate, informed consent will also be taken from their custodian.

Conditions

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Ventricular Tachycardia

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Study Groups

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Ventricular tachycardia

Patients with ventricular tachycardia of unknown origin treated with an ICD.

No interventions assigned to this group

Family members

Family members (parents, siblings and children) for patients with results showing mutations in the calmodulin genes.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Patients with ventricular tachycardia of unknown origin that have been treated with an ICD
* Signed and dated informed consent

Exclusion Criteria

\- Inability to provide informed consent
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Region Örebro County

OTHER

Sponsor Role lead

Responsible Party

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Ole Frobert, MD, PhD

MD, PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Ole Fröbert, MD, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Department of Cardiology, Örebro University Hospital, Örebro, Sweden

Locations

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Department of Cardiology, Örebro University Hospital

Örebro, , Sweden

Site Status

Countries

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Sweden

Other Identifiers

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Protocol no: 2012-11

Identifier Type: -

Identifier Source: org_study_id

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