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Gene Expression in Patients With Epiretinal Membranes

NCT ID: NCT01946451

Last Updated: 2013-09-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Study Classification

OBSERVATIONAL

Study Start Date

2012-06-30

Study Completion Date

2013-12-31

Brief Summary

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The purpose of this study was to investigate the expression of selected genes both in epiretinal membranes (ERMs) and peripheral blood mononuclear cells (PBMCs) from patients with primary and secondary epiretinal membranes in proliferative diabetic retinopathy. Possible correlations between messenger ribonucleic acid (mRNA) levels of these genes were also identified.

Detailed Description

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Conditions

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Proliferative Diabetic Retinopathy

Keywords

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idiopathic epiretinal membranes secondary epiretinal membranes

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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Idiophatic ERMs

No interventions assigned to this group

Secondary ERMs

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Caucasian race,
* both males and females,
* aged ≥ 55 years,
* suffering from idiopathic ERMs or secondary ERMs in proliferative diabetic retinopathy (PDR).
* Presence of ERM was proven in optical coherence tomography (OCT) examination.

Exclusion Criteria

* aged \< 55 years,
* systemic connective tissue disease,
* active inflammatory process
Minimum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medical University of Silesia

OTHER

Sponsor Role lead

Responsible Party

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Dorota Romaniuk

MD

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Medical University of Silesia

Katowice, , Poland

Site Status

Countries

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Poland

Other Identifiers

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SilesianMU

Identifier Type: -

Identifier Source: org_study_id