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Propolis In The Treatment Of Periodontitis

NCT ID: NCT01943877

Last Updated: 2013-09-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-12-31

Study Completion Date

2013-10-31

Brief Summary

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This study was conducted to evaluate by clinical and microbiological parameters the effect of locally delivered propolis as an adjunct to scaling and root planing in the treatment of chronic periodontitis.

Detailed Description

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Materials and Methods: 20 subjects diagnosed with chronic periodontitis were recruited to participate in split-mouth design and provided informed consent. Subgingival plaque sampling and clinical recording at baseline, 15 days and 1 month was performed. The patients received scaling and root planing, followed by Propolis administration subgingivally in the test sites. Significant differences between test and control were evaluated using the Mann-Whitney U test and Wilcoxon rank test.

Conditions

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Chronic Periodontitis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Propolis

Group Type EXPERIMENTAL

scaling root planing

Intervention Type PROCEDURE

scaling root planing

Propolis

Intervention Type DRUG

experimental

scaling and root planing

Group Type SHAM_COMPARATOR

scaling root planing

Intervention Type PROCEDURE

scaling root planing

Interventions

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scaling root planing

scaling root planing

Intervention Type PROCEDURE

Propolis

experimental

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* good general health
* chronic periodontitis
* minimum of 20 natural teeth with at least one pocket per quadrant
* probing depth (PD) between 5 and 8 mm.

Exclusion Criteria

* subgingival instrumentation within 3 months
* antibiotic therapy within 3 months prior to the start of the study;
* smokers
* pregnant or nursing women
* intolerance or allergy to honey products
Minimum Eligible Age

25 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Rajarajeswari Dental College & Hospital

OTHER

Sponsor Role lead

Responsible Party

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NEHAL N SANGHANI, mds

DR.

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Rajarajeswari Dental College and Hospital

Bangalore, Karnataka, India

Site Status

Countries

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India

Other Identifiers

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971987

Identifier Type: -

Identifier Source: org_study_id