Radiotherapy Alternates Human Epidermal Growth Factor 2 (Her2) Expression in Human Breast Cancer

NCT ID: NCT01934478

Last Updated: 2023-03-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

5 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-08-31

Study Completion Date

2022-12-30

Brief Summary

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Based on fundamental study (in Vitro and in Vivo, Pro. Jianjian Li), Her2 expression would be changed from negative to positive by cancer irradiation with liner-accelerator at dose 6GY or up. The propose of this study is to reveal the irradiation result on Her2 expression in human breast cancer.

Detailed Description

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Conditions

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Human Epidermal Growth Factor 2 Negative Carcinoma of Breast

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* histological confirmed advanced breast cancer
* cancer sample can be obtained by fine needle biopsy
* IHC and FISH confirmed Her2 negative
* radiotherapy indication for local residual cancer

Exclusion Criteria

* no radiotherapy indication
* patient refuse
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Qingdao Central Hospital

OTHER

Sponsor Role lead

Responsible Party

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Youxin Ji

Chief, Department of Oncology

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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ketao lan, M.D.

Role: STUDY_CHAIR

Qingdao Health Bereau

Locations

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Qingdao Central Hospital, Qingdao Cancer Hospital

Qingdao, Shandong, China

Site Status

Countries

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China

Other Identifiers

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QCH20130823-2

Identifier Type: -

Identifier Source: org_study_id

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