Non-antibiotic Prescribing for Acute Upper Respiratory Tract Infection

NCT ID: NCT01930955

Last Updated: 2023-05-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Clinical Phase

NA

Study Classification

INTERVENTIONAL

Study Start Date

2011-08-01

Study Completion Date

2022-12-30

Brief Summary

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Some acute upper respiratory tract infection(AURI) in children is characterized by fever and vomiting,and it is one common reason for visiting a pediatrician. White blood count(WBC) usually increased in this children patients,hence antibiotics are often prescribed properly assumed. In the present study, it was hypothesized that it was not necessary to prescribe amoxicillin for the children.

Detailed Description

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After inclusion of eligible children patients,one group was prescribed amoxicillin,and another not.

Conditions

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Acute Upper Respiratory Tract Infection

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Amoxicillin

Amoxicillin were given to the children with acute upper respiratory tract infection characterized by fever and vomiting.

Group Type ACTIVE_COMPARATOR

Amoxicillin

Intervention Type DRUG

β-lactam antibiotics

control

Non-antibiotics were given to the children with acute upper respiratory tract infection characterized by fever and vomiting.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Amoxicillin

β-lactam antibiotics

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Acute upper respiratory tract infection
* Fever
* Vomiting
* Increased white blood cell

Exclusion Criteria

* 0ther symptoms of digestive system
* Headache
Minimum Eligible Age

1 Year

Maximum Eligible Age

3 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Daping Hospital and the Research Institute of Surgery of the Third Military Medical University

OTHER

Sponsor Role lead

Responsible Party

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Chen Long,MD

Prof;MD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Long Chen, MD

Role: PRINCIPAL_INVESTIGATOR

Daping Hospital and the Research Institute of Surgery of the Third Military Medical University

Locations

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Department of Pediatrics, Daping Hospital, Research Institute of Surgery, Third Military Medical University

Chongqing, Chongqing Municipality, China

Site Status

Countries

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China

Other Identifiers

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AURI

Identifier Type: -

Identifier Source: org_study_id

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