Effects of Pepper Gas Exposure in Non-combatant Bystanders.

NCT ID: NCT01922700

Last Updated: 2014-07-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

298 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-04-30

Study Completion Date

2013-10-31

Brief Summary

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Pepper sprays and pepper gas grenades are used by riot police at various places in the world for crowd control. Data about the acute effects based on human studies is extremely scarce. Kashmir valley in the northern Indian state of Jammu \& Kashmir has witnessed political turmoil for the past 22 years and incidents of stone pelting are common wherein groups of youth indulge in stone pelting at the security personnel. While there have been previous episodes of fatalities associated with incidents of firing by the security personnel; non lethal methods are adopted routinely now. These include lathis, water cannons, tear gas and more recently the pepper gas grenades. The pepper grenades explode in the area and the adverse effects are perceived by the population in the area too who are even sitting in their homes. The study proposes to observe the health effects of the pepper gas exposure in non-combatant civilians.

Detailed Description

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Eligibility:

History of exposure to a pepper grenade explosion.

Exclusion:

Participation in combat operation/ stone pelting/ demonstration.

Conditions

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Cough Irritation in Throat Irritation in Skin Lacrimation

Study Design

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Observational Model Type

ECOLOGIC_OR_COMMUNITY

Study Time Perspective

CROSS_SECTIONAL

Eligibility Criteria

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Inclusion Criteria

All participants with a history of exposure to pepper gas grenade explosion

Exclusion Criteria

Combatant role while exposure
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Sheri Kashmir Institute of Medical Sciences

OTHER

Sponsor Role lead

Responsible Party

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Parvaiz A Koul

Professor & Head, Internal & Pulmonary Medicine

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Parvaiz Koul, MD, FRCP, FACP

Role: PRINCIPAL_INVESTIGATOR

Professor & Head, Internal & Pulmonary Medicine, SKIMS,Srinagar 190011 , J&K (India)

Locations

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SheriKashmir Institute of Medical Sciences

Srinagar, Jammu and Kashmir, India

Site Status

Countries

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India

References

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Cil H, Atilgan ZA, Islamoglu Y, Tekbas EO, Dostbil Z. Is the pepper spray a triggering factor in myocardial infarction? A case report. Eur Rev Med Pharmacol Sci. 2012 Mar;16 Suppl 1:73-4.

Reference Type BACKGROUND
PMID: 22582490 (View on PubMed)

Holopainen JM, Moilanen JA, Hack T, Tervo TM. Toxic carriers in pepper sprays may cause corneal erosion. Toxicol Appl Pharmacol. 2003 Feb 1;186(3):155-62. doi: 10.1016/s0041-008x(02)00015-7.

Reference Type RESULT
PMID: 12620368 (View on PubMed)

Vesaluoma M, Muller L, Gallar J, Lambiase A, Moilanen J, Hack T, Belmonte C, Tervo T. Effects of oleoresin capsicum pepper spray on human corneal morphology and sensitivity. Invest Ophthalmol Vis Sci. 2000 Jul;41(8):2138-47.

Reference Type RESULT
PMID: 10892855 (View on PubMed)

Other Identifiers

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PEPPER01

Identifier Type: -

Identifier Source: org_study_id

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