Does the Natural Medicinal Plant St John's Wort Affect the Glucose Tolerance in Healthy Individuals
NCT ID: NCT01921881
Last Updated: 2015-02-13
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
PHASE1
10 participants
INTERVENTIONAL
2013-09-30
2014-12-31
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Interaction Between St John's Wort and Metformin?
NCT01726764
Effect of Coccinia Cordifolia Extract on Blood Sugar of Newly Diagnosed Diabetics
NCT00502008
Efficacy Study Testing Herbal Extract on Metabolic Parameters in Subjects With Type 2 Diabetes
NCT00499148
Effect of Medicago Sativa on Oral Glucose Tolerance in Healthy Adults
NCT03714438
The Effect of a Botanical Plant Extract on Gut Health, Immunity and Metabolic Disorders in Healthy Adults
NCT03921333
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
NA
SINGLE_GROUP
NONE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
St John's wort
Subjects will undergo 3 oral glucose tolerance tests:
1. Without taking any St John's wort
2. After 3 weeks pretreatment with St John's wort
3. Minimum 6 weeks after last St John's wort ingestion
St John's wort
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
St John's wort
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Males
* Fasting plasma-glucose \< 7.0 mmol/L
* Glycosylated haemoglobin A1c within reference or clinically insignificant deviation hereof
* Body mass index \< 30 kg/m\^2
Exclusion Criteria
* Chronical or daily alcohol abuse
* Known liver disease
* Ingestion of drugs requiring prescription, except locally acting drugs
18 Years
40 Years
MALE
Yes
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
University of Southern Denmark
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Tore B. Stage
MSc Pharm
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Kim Brøsem, Professor, MD
Role: STUDY_DIRECTOR
University of Southern Denmark
Per Damkier, MD PhD
Role: PRINCIPAL_INVESTIGATOR
University of Southern Denmark
Tore B. Stage, MSc Pharm
Role: PRINCIPAL_INVESTIGATOR
University of Southern Denmark
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Department of Clinical Pharmacology, Institute of Public Health, University of Southern Denmark
Odense C, , Denmark
Countries
Review the countries where the study has at least one active or historical site.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
AKF-385
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.