Effect of Home-fortification With Sprinkles in Hematologic and Nutritional Status in Preschool Children in Medellín

NCT ID: NCT01917032

Last Updated: 2013-08-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE3

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-09-30

Study Completion Date

2013-12-31

Brief Summary

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Objective: To acquire the local scientific evidence, to evaluate the effects of micronutrient Sprinkles™ powder, both the nutritional status and haematological values in the vulnerable preschool population, to corroborate the reported benefits of the experiences in other countries.

Question: Will it improve the nutritional status and hematological levels after the home fortification with Sprinkles in children of two child care centres in the city of Medellin, in 2013?

Hypothesis: At the end of intervention, hematologic levels and anthropometric indicators will be better in the intervention group with Sprinkles, compared with the placebo group.

Design: Randomized clinical trial, triple-blind and placebo-controlled.

Participants: Two groups of 50 children each, aged between 5 and 59 months, not anemic or with severe malnourished, full-time assistants to two children's centres that have the same alimentation menu.

Intervention: The daily diet will be supplemented with sprinkles in one of the children's centres and will be compared anthropometric and hematological values before and after with a group receiving the same diet with placebo.

Outcome measures: Nutritional status (anthropometric measures) and haematological values (hemoglobin, ferritin, transferrin and folate).

Detailed Description

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Conditions

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Malnutrition

Keywords

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Trace Elements Preschool Malnutrition Fortified Food

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Sprinkles

Micronutrient Powder Sprinkles 1 gram orally on weekdays during 11 weeks

Group Type ACTIVE_COMPARATOR

Sachets containing a blend of micronutrients in powder form (Iron, Zinc, Folic Acid, Vitamin A and C), sprinkled onto home made food

Intervention Type DIETARY_SUPPLEMENT

1 g orally on weekdays during 11 weeks

Placebo

Maltodextrin 1 gram orally on weekdays during 11 weeks

Group Type PLACEBO_COMPARATOR

placebo

Intervention Type DIETARY_SUPPLEMENT

Interventions

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Sachets containing a blend of micronutrients in powder form (Iron, Zinc, Folic Acid, Vitamin A and C), sprinkled onto home made food

1 g orally on weekdays during 11 weeks

Intervention Type DIETARY_SUPPLEMENT

placebo

Intervention Type DIETARY_SUPPLEMENT

Other Intervention Names

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Chispitas Sprinkles

Eligibility Criteria

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Inclusion Criteria

* Assistance to children's centres full day (8 hours).
* Age 5 to 59 months.

Exclusion Criteria

* Anemia (hemoglobin less than 11 g / dl).
* Current supplementation with a product formulated by a health professional as a part of a nutritional recovery.
* Denial for informed consent signing by parents or legal guardians.
* Diagnosis of severe acute malnutrition by anthropometric measurements.
Minimum Eligible Age

5 Months

Maximum Eligible Age

59 Months

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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CES University

OTHER

Sponsor Role lead

Responsible Party

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Cristian Vargas G. MD

Student

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Cristian Vargas, MD

Role: PRINCIPAL_INVESTIGATOR

CES University

Juliana Orozco, Nutricionist

Role: PRINCIPAL_INVESTIGATOR

CES University

Juliana Sánchez, Dentist

Role: STUDY_CHAIR

CES University

Liliana Montoya, Epidemiology

Role: STUDY_DIRECTOR

CES University

Javier Chica, Veterinarian

Role: STUDY_CHAIR

CES University

Maylen Rojas, Epidemiology

Role: STUDY_CHAIR

CES University

Óscar Villada, MD

Role: STUDY_CHAIR

CES University

Alejandro Díaz, Pediatrist

Role: STUDY_CHAIR

CES University

Locations

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Fundación de Atención a la Niñez (FAN)

Medellín, Ant, Colombia

Site Status

Countries

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Colombia

Central Contacts

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Cristian Vargas, MD

Role: CONTACT

Phone: 573006099044

Email: [email protected]

Juliana Orozco, Nutritionist

Role: CONTACT

Phone: 573205371487

Email: [email protected]

Facility Contacts

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Viviana Ramírez, Nutricionist

Role: primary

Other Identifiers

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SPRINK001

Identifier Type: -

Identifier Source: org_study_id