Study Results
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Basic Information
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COMPLETED
353 participants
OBSERVATIONAL
2013-08-31
2018-12-31
Brief Summary
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Detailed Description
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Blood pressure measurements are being obtained with ambulatory 24-hour BP monitoring (ABPM) every 20 minutes within 24 hours of admission using automated oscillometric device (TM2430, A\&D Company Ltd) during day-time (7:00-22:59) and night-time (23:00-6:59).
Several clinical, laboratory and imaging parameters are prospectively registered. Also, patients' medical history, previous medical treatment and cardiovascular risk factors are registered.
Functional outcome is assessed by the modified Rankin Scale score at 3 months. Also, stroke recurrence and cardiovascular and all-cause mortality will be assessed.
Conditions
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Study Design
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COHORT
PROSPECTIVE
Eligibility Criteria
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Inclusion Criteria
* Admission within 24 after the onset of symptoms
Exclusion Criteria
* Intracerebral hemorrhage
* Subarachnoid hemorrhage
* Cerebral sinus venous thrombosis
* Stroke mimics
* Late admission (\>24 hours after stroke onset)
18 Years
ALL
No
Sponsors
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A & D Company Limited
INDUSTRY
Aristotle University Of Thessaloniki
OTHER
Responsible Party
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Nikolaos Kakaletsis
MD, MSc, Resident in Internal Medicine, AHEPA University Hospital
Principal Investigators
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Apostolos I. Hatzitolios, MD, PhD
Role: STUDY_DIRECTOR
Aristotle University of Thessaloniki, AHEPA University Hospital
Locations
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Second Department of Internal Medicine, Medical School, University of Ioannina, University Hospital of Ioannina
Ioannina, , Greece
Department of Medicine, Medical School, University of Thessaly, University Hospital of Larissa
Larissa, , Greece
First Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, AHEPA University Hospital
Thessaloniki, , Greece
Countries
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References
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Kakaletsis N, Ntaios G, Milionis H, Haidich AB, Makaritsis K, Savopoulos C, Berge E, Hatzitolios AI. Prognostic value of 24-h ABPM in acute ischemic stroke for short-, medium-, and long-term outcome: a systematic review and meta-analysis. Int J Stroke. 2015 Oct;10(7):1000-7. doi: 10.1111/ijs.12609. Epub 2015 Aug 18.
Kakaletsis N, Ntaios G, Milionis H, Karagiannaki A, Chouvarda I, Dourliou V, Chytas A, Hatzitolios AI, Savopoulos C. Prognostic significance of 24-h blood pressure and variability indices in the outcome of acute ischaemic stroke. Intern Med J. 2023 Jul;53(7):1137-1146. doi: 10.1111/imj.15834. Epub 2022 Sep 12.
Kakaletsis N, Ntaios G, Milionis H, Protogerou AD, Karagiannaki A, Chouvarda I, Dourliou V, Ladakis I, Kaiafa G, Daios S, Doumas M, Savopoulos C. Time of blood pressure in target range in acute ischemic stroke. J Hypertens. 2023 Feb 1;41(2):303-309. doi: 10.1097/HJH.0000000000003331. Epub 2022 Nov 25.
Kakaletsis N, Ntaios G, Milionis H, Karagiannaki A, Chouvarda I, Dourliou V, Ladakis I, Kaiafa G, Vemmos K, Savopoulos C. Midday Dipping and Circadian Blood Pressure Patterns in Acute Ischemic Stroke. J Clin Med. 2023 Jul 21;12(14):4816. doi: 10.3390/jcm12144816.
Karagiannaki A, Kakaletsis N, Chouvarda I, Dourliou V, Milionis H, Savopoulos C, Ntaios G. Association between antihypertensive treatment, blood pressure variability, and stroke severity and outcomes in acute ischemic stroke. J Clin Neurosci. 2024 Jul;125:51-58. doi: 10.1016/j.jocn.2024.05.014. Epub 2024 May 15.
Other Identifiers
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AUTH-A7399-1862013
Identifier Type: -
Identifier Source: org_study_id
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