Blood Pressure Variability and the Prognosis of Ischemic Stroke With Intracranial Artery Stenosis
NCT ID: NCT01665235
Last Updated: 2012-08-15
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
200 participants
INTERVENTIONAL
2012-08-31
2014-08-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
SINGLE_GROUP
TREATMENT
NONE
Study Groups
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amlodipine
The amlodipine - based antihypertensive treatment group (you can add a diuretic or other )
Amlodipine
The amlodipine - based antihypertensive treatment group (you can add a diuretic or other )
Aspirin or Clopidogrel
aspirin 100mg / d or Clopidogrel 75mg / d (anti-platelet agents)
Atorvastatin
Atorvastatin 10 - 40mg / d ( statin therapy)
ACEI / ARB
ACEI / ARB -based antihypertensive treatment group ( you can add the B - blockers or other)
ACEI / ARB
ACEI / ARB -based antihypertensive treatment group ( you can add the B - blockers or other)
Aspirin or Clopidogrel
aspirin 100mg / d or Clopidogrel 75mg / d (anti-platelet agents)
Atorvastatin
Atorvastatin 10 - 40mg / d ( statin therapy)
Interventions
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Amlodipine
The amlodipine - based antihypertensive treatment group (you can add a diuretic or other )
ACEI / ARB
ACEI / ARB -based antihypertensive treatment group ( you can add the B - blockers or other)
Aspirin or Clopidogrel
aspirin 100mg / d or Clopidogrel 75mg / d (anti-platelet agents)
Atorvastatin
Atorvastatin 10 - 40mg / d ( statin therapy)
Eligibility Criteria
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Inclusion Criteria
* with intracranial artery stenosis in ischemic stroke
* the diagnosis of ischemic cerebrovascular disease are in line with the diagnostic criteria developed by the Chinese Medical Association Fourth National Cerebrovascular Disease Conference
* the patient admitted to hospital receive at least one examination like cranial MRI + DWI, MRA and TCD examination, clearly associated with intracranial arterial stenosis
* MRS score ≤ 3 points
Exclusion Criteria
* associated with significant emotional disorders, cognitive impairment or other mental disorders can not be partners
* severe occlusion of Unilateral intracranial arteries ( over 90 % ) or bilateral stenosis more than 70%
* With extracranial artery stenosis, especially carotid and vertebral artery stenosis .
* patients with extracranial artery stenosis or patients previously done neck or intracranial artery balloon dilation , stent forming surgery or carotid endarterectomy
* Incomplete clinical data collection in patients
18 Years
75 Years
ALL
No
Sponsors
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RenJi Hospital
OTHER
Responsible Party
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Shi Guowen
Principal Investigator
Principal Investigators
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Guowen Shi, MD
Role: PRINCIPAL_INVESTIGATOR
RenJi Hospital
Locations
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RenJi Hospital
Shanghai, Shanghai Municipality, China
Countries
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Central Contacts
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Other Identifiers
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RenJiH-20120804
Identifier Type: -
Identifier Source: org_study_id
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