Impact of Chronic Air Pollution on Non-cystic Fibrosis Bronchiectasis

NCT ID: NCT01906047

Last Updated: 2013-07-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

189 participants

Study Classification

OBSERVATIONAL

Study Start Date

2006-06-30

Study Completion Date

2013-04-30

Brief Summary

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We aim at investigation the impact of chronic air pollution exposure on non-cystic fibrosis bronchiectasis outcome.

Detailed Description

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* Patient files will be search for time of death and cause of death.
* Other variables will be collected: bacterial culture results, therapy, gender, age, etc.
* These data will be linked with pollution data: trafic load, distance to major road, etc.

Conditions

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Bronchiectasis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* HRCT diagnosis of bronchiectasis
* recurrent infections or chronic sputum production
* patients between 18 and 65 years old.

Exclusion Criteria

* Cystic Fibrosis
* Tumoral disease
* Traction bronchiectasis due to interstitial lung disease
* patients older than 65 years or younger than 18 years at recruitment
* COPD
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Universitaire Ziekenhuizen KU Leuven

OTHER

Sponsor Role lead

Responsible Party

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Dr. Lieven Dupont

Prof. Dr. Lieven Dupont

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Lieven J Dupont, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

UZ Leuven

Pieter C Goeminne, MD

Role: PRINCIPAL_INVESTIGATOR

UZ Leuven

Locations

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UZ Leuven

Leuven, Vlaams-Brabant, Belgium

Site Status

Countries

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Belgium

References

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Goeminne PC, Bijnens E, Nemery B, Nawrot TS, Dupont LJ. Impact of traffic related air pollution indicators on non-cystic fibrosis bronchiectasis mortality: a cohort analysis. Respir Res. 2014 Sep 3;15(1):108. doi: 10.1186/s12931-014-0108-z.

Reference Type DERIVED
PMID: 25183428 (View on PubMed)

Other Identifiers

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NCFB chronic pollution

Identifier Type: -

Identifier Source: org_study_id

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