PEL-1235_REN-0176-I (Pelicon)

NCT ID: NCT01904045

Last Updated: 2018-09-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

51 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-05-31

Study Completion Date

2018-08-31

Brief Summary

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Aim of this study is to investigate whether in patients following kidney transplantation (\>6 months after transplantation), the intra-patient variability of levels of tacrolimus is comparable after administration of tacrolimus twice daily (Prograf) to tacrolimus once daily (Advagraf), with each regimen for 3 months.

Detailed Description

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Conditions

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Immunosuppression After Kidney Transplantation

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Interventions

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tacrolimus Advagraf

intake of Advagraf once daily for 3 months

Intervention Type OTHER

tacrolimus Prograf

intake of Prograf twice daily for 3 months

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* signed written informed consent
* male or female patient ≥ 18years of age
* Patient has received a kidney transplantation at least 6 months prior to inclusion into the study
* No acute rejection episodes for at least 3 months
* PRG through level and dosing stable for at least 1 month
* Patient is capable of understanding the purpose and risks of the study, has been fully informed and has given written informed consent to participate in the study

Exclusion Criteria

* Acute rejection episodes within the last 3 months prior to study entry
* Unstable PRG trough level or dose change in the month before study entry
* History of noncompliance to medical regimens
* Patients unwilling to or unable to comply with the protocol
* Treatment with another investigational product during this study or during the last 30 days prior to study start
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Technical University of Munich

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Klinikum rechts der Isar, Department of Nephrology

Munich, Bavaria, Germany

Site Status

Countries

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Germany

Other Identifiers

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PEL-1235_REN-0176-I

Identifier Type: -

Identifier Source: org_study_id

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