Herbal Tonic Fertile Supplement(ZO2C5)

NCT ID: NCT01895816

Last Updated: 2013-07-12

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: PHASE3
• Total Enrollment: 1 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2012-06-30
• Study Completion Date: 2012-06-30

Brief Summary

The purpose of this study is to determine whether the effect of mixed herbals drug (citrus, citrolus vol, lan, carrot seed, zingiber, onion, basil, cinnamon) administration on male infertility: oligospermia

Detailed Description

In the last few years, a marked decrease in the quality of semen has been reported. Infertility is one of the major health problems in 10 to 15% of couples' lives; from which approximately 50% of couple's infertility is due to Male factors. The aim of the present study was to evaluate an herbal mixed effects on spermatogenesis and the normal production of sperm. Researchers have reported that using antioxidants and vitamins A, B, C, E, flavonoids, Sulfur compounds, terpenoids and phenolic compounds in the daily diet can protect sperm. In this study the investigators aimed to assess synergistic effect of these herbal compounds in male Infertility. 700 mg tablet for 180 consequence days/daily will be advising, for 40 patients semen samples in 1th and 180 day after treatment will take, in andrology lab according WHO method:samples put into 2 mL of medium (Hams F10) containing 0.5% bovine serum albumin. After 5 min incubation at 37oC (with 5% CO), the sperm samples were determined using the standard haemocytometric method, and sperm motility was analyzed by microscope (Olympus IX70) at 10 field and reported as the mean of motile sperm according to WHO methods . The sperm abnormality was evaluated according to the standard method of Narayana .Briefly, smears of the sperm suspension were made on clean glass slides and stained with periodic acid-Schiff's reaction haematoxylin. The stained smears were observed under a light microscopic with 40× magnification. The sperms were classified into normal and abnormal. The total sperm abnormality was expressed as percentage incidence. Other biochemical tests will be doing according the our research protocol and thesis for blood samples for measure LH, Testosterone, TAC, Glc and Cholesterol.

Conditions

Male Infertility

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: SUPPORTIVE_CARE
• Blinding Strategy: SINGLE

Study Groups

fertility coated tablet

700 mg fertility coated tablet containing 8 herbal powders by mouth every 12 hours for 180 days

Group Type: EXPERIMENTAL

coated tablet

Intervention Type: DIETARY_SUPPLEMENT

this supplement contains 700 mg of 8 natural herbals: Citrus \& ZINGIBER OFFICINALE \& Onion \& Ocimum basilicum \& Cinnamomum zelanicum \& Citrullus lanatus \& Citrullus vulgaris \& Daucus carota

Interventions

coated tablet

this supplement contains 700 mg of 8 natural herbals: Citrus \& ZINGIBER OFFICINALE \& Onion \& Ocimum basilicum \& Cinnamomum zelanicum \& Citrullus lanatus \& Citrullus vulgaris \& Daucus carota

Intervention Type: DIETARY_SUPPLEMENT

Other Intervention Names

Dietry supplement

Eligibility Criteria

Inclusion Criteria

• all patients suffering from oligospermia are included

Exclusion Criteria

• any diseases

• Minimum Eligible Age: 25 Years
• Maximum Eligible Age: 50 Years
• Eligible Sex: MALE
• Accepts Healthy Volunteers: Yes

Sponsors

Islamic Azad University of Tabriz

OTHER

Sponsor Role: collaborator

Tabriz University

OTHER

Sponsor Role: collaborator

Arash Khaki

OTHER

Sponsor Role: lead

Responsible Party

Arash Khaki

Clinical professor. Women's Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Responsibility Role: SPONSOR_INVESTIGATOR

Principal Investigators

Arash Khaki, PhD

Role: STUDY_DIRECTOR

Women Reproductive Health Research Center,Tabriz University of medical Sciences

Locations

Womens Reproductive Health Research Center,Tabriz University Of Medical Sciences,Iran

Tabriz, Azarbyjan, Iran

Countries

Iran

Other Identifiers

WRHRC-9026

Identifier Type: -

Identifier Source: org_study_id