Assessment of Nutritional Status After Gastric Bypass Surgery

NCT ID: NCT01891591

Last Updated: 2013-07-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

16 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-03-31

Study Completion Date

2011-12-31

Brief Summary

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This study is aimed at assessing how Roux-en-Y gastric bypass (RYGP) impacts on energy and nutrients' intake, energy expenditure, and nutritional status in obese patients. It will try quantitate energy and protein balance after RYGP, and to identify how RYGP effects the intake of various common dietary protein sources 16 female patients with BMI \> 40 kg/m2 and on a waiting list for bariatric surgery will be included. The following measurements will be performed before, and 1, 3, 6, 12, and 36 months after RYGP

* body weight
* body composition (bio impedancemetry)
* basal metabolic rate (open circuit indirect calorimetry)
* 24-hour urinary urea excretion
* fasting blood chemistry
* energy and macronutrient's intake (3-day dietary recall)

Detailed Description

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Conditions

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Obesity Nutritional Deficiencies

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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obese female subjects

16 obese female subjects with BMI \> 40 kg/m2 on a waiting list for bariatric surgery

Roux-en-Y gastric bypass (RYGP)

Intervention Type PROCEDURE

Interventions

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Roux-en-Y gastric bypass (RYGP)

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* age 18-65 years
* gender: females
* body mass index \>35 kg/m2

Exclusion Criteria

* GI tract diseases
* endocrine diseases
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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University of Lausanne

OTHER

Sponsor Role lead

Responsible Party

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Luc Tappy, MD

professor of Physiology

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Vittorio Giusti, MD

Role: PRINCIPAL_INVESTIGATOR

CHUV

Locations

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Clinical Research Centre, CHUV

Lausanne, , Switzerland

Site Status

Countries

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Switzerland

References

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Chakhtoura MT, Nakhoul NF, Akl EA, Safadi BY, Mantzoros CS, Metzendorf MI, El-Hajj Fuleihan G. Oral vitamin D supplementation for adults with obesity undergoing bariatric surgery. Cochrane Database Syst Rev. 2024 Oct 1;10(10):CD011800. doi: 10.1002/14651858.CD011800.pub2.

Reference Type DERIVED
PMID: 39351881 (View on PubMed)

Giusti V, Theytaz F, Di Vetta V, Clarisse M, Suter M, Tappy L. Energy and macronutrient intake after gastric bypass for morbid obesity: a 3-y observational study focused on protein consumption. Am J Clin Nutr. 2016 Jan;103(1):18-24. doi: 10.3945/ajcn.115.111732. Epub 2015 Dec 16.

Reference Type DERIVED
PMID: 26675775 (View on PubMed)

De Giorgi S, Campos V, Egli L, Toepel U, Carrel G, Cariou B, Rainteau D, Schneiter P, Tappy L, Giusti V. Long-term effects of Roux-en-Y gastric bypass on postprandial plasma lipid and bile acids kinetics in female non diabetic subjects: A cross-sectional pilot study. Clin Nutr. 2015 Oct;34(5):911-7. doi: 10.1016/j.clnu.2014.09.018. Epub 2014 Sep 26.

Reference Type DERIVED
PMID: 25306425 (View on PubMed)

Other Identifiers

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39/08

Identifier Type: -

Identifier Source: org_study_id

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