CT in Diagnosing Patients With Lung Cancer

NCT ID: NCT01888510

Last Updated: 2016-07-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-05-31

Study Completion Date

2016-06-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This clinical trial studies computed tomography (CT) in diagnosing patients with lung cancer. Diagnostic procedures, such as CT, may help find and diagnose lung cancer.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

PRIMARY OBJECTIVES:

I. Conduct a prospective clinical imaging study to quantify the amount of inter- and intra-physician contouring variability on four dimensional (4D) CT, active breathing control (ABC) CT, free breathing CT, and free breathing and ABC cone beam (CB)CT.

II. Quantify the magnitude and distribution of target and organ at risk volume variations between the different imaging modalities.

III. Determine dosimetric changes related to contouring variations for tumor and normal tissue.

OUTLINE:

Patients undergo conventional free breathing CT, 4D CT, ABC CT, ABC CBCT, and free breathing CBCT before undergoing radiation therapy.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Lung Cancer

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Diagnostic (imaging studies)

Patients undergo conventional free breathing CT, 4D CT, ABC CT, ABC CBCT, and free breathing CBCT before undergoing radiation therapy.

Group Type EXPERIMENTAL

computed tomography

Intervention Type PROCEDURE

Undergo conventional free breathing CT

4-dimensional computed tomography

Intervention Type PROCEDURE

Undergo 4D CT

computed tomography

Intervention Type PROCEDURE

Undergo ABC CT

cone-beam computed tomography

Intervention Type PROCEDURE

Undergo ABC CBCT

cone-beam computed tomography

Intervention Type PROCEDURE

Undergo free breathing CBCT

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

computed tomography

Undergo conventional free breathing CT

Intervention Type PROCEDURE

4-dimensional computed tomography

Undergo 4D CT

Intervention Type PROCEDURE

computed tomography

Undergo ABC CT

Intervention Type PROCEDURE

cone-beam computed tomography

Undergo ABC CBCT

Intervention Type PROCEDURE

cone-beam computed tomography

Undergo free breathing CBCT

Intervention Type PROCEDURE

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

tomography, computed 4D-CT tomography, computed

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Measurable disease on CT scan
* Patients with lung cancer visible on CT who are scheduled to receive external beam radiation treatment will be eligible for this study
* Patients must be able to perform ABC procedures

Exclusion Criteria

* Patients requiring continuous supplemental oxygen due to the requirement of spirometry during all imaging studies
* No vulnerable populations will be enrolled (prisoners, children, pregnant females or institutionalized individuals)
* Women of childbearing potential will undergo a pregnancy test
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Virginia Commonwealth University

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Elizabeth Weiss, M.D.

Role: PRINCIPAL_INVESTIGATOR

Virginia Commonwealth University

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Virginia Commonwealth University/Massey Cancer Center

Richmond, Virginia, United States

Site Status

Countries

Review the countries where the study has at least one active or historical site.

United States

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

NCI-2013-01163

Identifier Type: REGISTRY

Identifier Source: secondary_id

MCC-15032

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Study of Use of CTC in NSCLC
NCT01990651 UNKNOWN
Early Detection of Lung Cancer
NCT03181256 ACTIVE_NOT_RECRUITING
Lung Screening Study
NCT00006382 COMPLETED NA