Fetuin A in Hashimoto Thyroiditis

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

97 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-05-31

Study Completion Date

2012-10-31

Brief Summary

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Fetuin-A levels are reported to be low as a negative acute phase reactant in systemical inflammatory situations. Hashimoto thyroiditis is characterized with inflammation. In this study, we hypothesised that the serum fetuin A levels could be found to be low due to inflammation in patients with Hashimoto thyroiditis

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Detailed Description

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Patients ≥ 20 years of age being followed up at the outpatient clinics of the Internal Medicine Department in Medeniyet University Goztepe Training and Research Hospital and fulfilling the eligibility criteria will be included in the study. Approval of the local ethics committee and informed consent of the participants will be received for the study. The study is conducted in accordance with the Declaration of Helsinki. Demographic characteristics, concomitant diseases, smoking and alcohol drinking habits, concomitant medication usage, anthropometric and biochemistry data of the eligible patients will be recorded. Patient group will consist of patients with newly diagnosed Hashimoto thyroiditis and the control group will consist of healthy volunteers.

Groups will be compared according to their demographic, an¬thropometric and biochemistry data and serum fetuin-A levels. In order to detect the relationship between the serum fetuin-A levels and clinical features, correlation analyses will be done.

Conditions

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Hashimoto Thyroiditis

Study Design

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Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Group of Hashimoto thyroiditis patients

No interventions assigned to this group

Healty control group

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* patients newly diagnosed with Hashimoto thyroiditis

Exclusion Criteria

* Acute infection
* Acute or chronic inflammatory disease
* Anti-inflammatory treatment (non-steroidal anti-inflammatory, corticosteroids etc.)
* Hypoxic situations (chronic obstructive pulmonary disease etc.)
* Severe heart, kidney and liver disease
* Pregnancy
* Endocrine disorders
* Malignancy
* Usage of drug that affects thyroid hormone levels

Minimum Eligible Age

20 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No