Ex-Vivo Reversion of Platelet Inhibition Induced by Prasugrel

NCT ID: NCT01839968

Last Updated: 2014-08-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

32 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-09-30

Study Completion Date

2014-01-31

Brief Summary

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The purpose of this ex-vivo study is to estimate the optimal platelet quantity necessary to reverse the antiplatelet effects of prasugrel.

Detailed Description

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Conditions

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Acquired Platelet Disorder

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Study patients

Acute coronary syndrome patients with a recent loading dose of prasugrel (6-24h)

Ex vivo addition of normal platelet rich plasma to prasugrel-treated platelet rich plasma

Intervention Type OTHER

Interventions

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Ex vivo addition of normal platelet rich plasma to prasugrel-treated platelet rich plasma

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Acute coronary syndrome
* Prasugrel loading dose 6-24h before inclusion

Exclusion Criteria

* Clopidogrel loading dose
* GPIIbIIIa use within 10 days before inclusion
* Known congenital thrombopathy and/or congenital coagulation defect
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Geneva

OTHER

Sponsor Role lead

Responsible Party

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Fanny Bonhomme

MD

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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University Hospital of Geneva

Geneva, Canton of Geneva, Switzerland

Site Status

Countries

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Switzerland

Other Identifiers

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11-117

Identifier Type: -

Identifier Source: org_study_id

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