Pinnacle Metal-on-Metal 522 Post-Market Surveillance Study

NCT ID: NCT01828801

Last Updated: 2016-09-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

276 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-03-31

Study Completion Date

2016-08-31

Brief Summary

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The purpose of this clinical study is to evaluate blood metal ion levels as a function of time of implantation for the Pinnacle Acetabular MoM system.

Detailed Description

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Conditions

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Pinnacle Metal-on-Metal Revised Pinnacle Metal-on-Metal Adverse Local Tissue Reaction Metal Ions Total Hip Arthroplasty

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Pre-Op

Pre-operative patients who will undergo a total hip replacement.

No interventions assigned to this group

1 year post-op

Patients that underwent a Pinnacle Metal-on-Metal (MoM) total hip replacement (THR) and at the time of enrollment, based on their date of surgery, were 1 year post-operative . Alternatively these are patients who have had their Pinnacle Metal-on-Metal hip revised but if they were not revised, would have fallen into this time point.

Pinnacle Metal-on Metal

Intervention Type DEVICE

All patients that are post-operative will have undergone total hip arthroplasty with the Pinnacle Metal-on-Metal device

2 year post-op

Patients that underwent a Pinnacle Metal-on-Metal (MoM) total hip replacement (THR) and at the time of enrollment, based on their date of surgery, were 2 years post-operative . Alternatively these are patients who have had their Pinnacle Metal-on-Metal hip revised but if they were not revised, would have fallen into this time point.

Pinnacle Metal-on Metal

Intervention Type DEVICE

All patients that are post-operative will have undergone total hip arthroplasty with the Pinnacle Metal-on-Metal device

3 year post-op

Patients that underwent a Pinnacle Metal-on-Metal (MoM) total hip replacement (THR) and at the time of enrollment, based on their date of surgery, were 3 years post-operative . Alternatively these are patients who have had their Pinnacle Metal-on-Metal hip revised but if they were not revised, would have fallen into this time point.

Pinnacle Metal-on Metal

Intervention Type DEVICE

All patients that are post-operative will have undergone total hip arthroplasty with the Pinnacle Metal-on-Metal device

4 year post-op

Patients that underwent a Pinnacle Metal-on-Metal (MoM) total hip replacement (THR) and at the time of enrollment, based on their date of surgery, were 4 years post-operative . Alternatively these are patients who have had their Pinnacle Metal-on-Metal hip revised but if they were not revised, would have fallen into this time point.

Pinnacle Metal-on Metal

Intervention Type DEVICE

All patients that are post-operative will have undergone total hip arthroplasty with the Pinnacle Metal-on-Metal device

5 year post-op

Patients that underwent a Pinnacle Metal-on-Metal (MoM) total hip replacement (THR) and at the time of enrollment, based on their date of surgery, were 5 years post-operative . Alternatively these are patients who have had their Pinnacle Metal-on-Metal hip revised but if they were not revised, would have fallen into this time point.

Pinnacle Metal-on Metal

Intervention Type DEVICE

All patients that are post-operative will have undergone total hip arthroplasty with the Pinnacle Metal-on-Metal device

6 year post-op

Patients that underwent a Pinnacle Metal-on-Metal (MoM) total hip replacement (THR) and at the time of enrollment, based on their date of surgery, were 6 years post-operative . Alternatively these are patients who have had their Pinnacle Metal-on-Metal hip revised but if they were not revised, would have fallen into this time point.

Pinnacle Metal-on Metal

Intervention Type DEVICE

All patients that are post-operative will have undergone total hip arthroplasty with the Pinnacle Metal-on-Metal device

7 year post-op

Patients that underwent a Pinnacle Metal-on-Metal (MoM) total hip replacement (THR) and at the time of enrollment, based on their date of surgery, were 7 years post-operative . Alternatively these are patients who have had their Pinnacle Metal-on-Metal hip revised but if they were not revised, would have fallen into this time point.

Pinnacle Metal-on Metal

Intervention Type DEVICE

All patients that are post-operative will have undergone total hip arthroplasty with the Pinnacle Metal-on-Metal device

8 year post-op

Patients that underwent a Pinnacle Metal-on-Metal (MoM) total hip replacement (THR) and at the time of enrollment, based on their date of surgery, were 8 years post-operative . Alternatively these are patients who have had their Pinnacle Metal-on-Metal hip revised but if they were not revised, would have fallen into this time point.

Pinnacle Metal-on Metal

Intervention Type DEVICE

All patients that are post-operative will have undergone total hip arthroplasty with the Pinnacle Metal-on-Metal device

Interventions

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Pinnacle Metal-on Metal

All patients that are post-operative will have undergone total hip arthroplasty with the Pinnacle Metal-on-Metal device

Intervention Type DEVICE

Other Intervention Names

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Pinnacle MoM Ultamet

Eligibility Criteria

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Inclusion Criteria

1. Able to (or capable of) provide written, voluntary consent to participate in the clinical investigation
2. Is willing and able to return for all protocol defined clinic visits
3. Subject has a combination of the following implants in the study hip (unless in pre-op cohort):

1. Pinnacle acetabular shell with or without Gription TM porous coating
2. M-specification cobalt-chrome femoral head or aSphere M-specification cobalt-chrome femoral head
3. Ultamet metal insert
4. One of the following stems

i. S-ROM ii. Corail iii. Tri-Lock iv. AML v. Summit vi. Prodigy vii. C-Stem
4. Subject has high quality films available for review that were taken within 12 months of the primary surgery of the following views:

1. Standing AP-Pelvis
2. Standing AP-Proximal Femur (if this view is not available but the AP-Pelvis shows the entire implant and greater trochanter, that is also acceptable)
3. Lauenstein Lateral Proximal Femur (Lateral-Femur)

Exclusion Criteria

1. The subject refuses to allow their medical records to be inspected by the Sponsor, representatives of the Sponsor, the medical office staff and/or representatives from FDA
2. The implanted hip components in the study hip (exclusive of cement), are not all DePuy components (unless in pre-op cohort)
3. The primary procedure occurred greater than 8 (eight) years ago (unless in pre-op cohort)
4. FOR PRE-OPERATIVE COHORT ONLY: the subject has a MoM contralateral hip
5. FOR PRE-OPERATIVE COHORT ONLY: the subject is undergoing a revision of the Ipsilateral hip
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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DePuy Orthopaedics

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Mary F Panozzo, BS

Role: STUDY_DIRECTOR

DePuy Synthes Joint Reconstruction

Locations

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Orange, California, United States

Site Status

Fort Collins, Colorado, United States

Site Status

Lone Tree, Colorado, United States

Site Status

Syracuse, New York, United States

Site Status

Charlotte, North Carolina, United States

Site Status

Durham, North Carolina, United States

Site Status

Cincinnatti, Ohio, United States

Site Status

Austin, Texas, United States

Site Status

Countries

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United States

Other Identifiers

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10017

Identifier Type: -

Identifier Source: org_study_id

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