Comparing Efficacy and Safety Between Eperisone a BID and a TID Regimen in Acute Low Back Pain Patients

NCT ID: NCT01806818

Last Updated: 2013-08-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

98 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-02-28

Study Completion Date

2013-07-31

Brief Summary

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Multi-center Study to Compare Efficacy and Safety between Eperisone a BID and a TID Regimen in Acute Low Back Pain Patients during 7 days.

Detailed Description

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Conditions

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Low Back Pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Eperisone 50mg BID

Administrate Eperisone 50mg tablet after the breakfast and dinner, and pacebo tablet after the lunch for 7 days

Group Type EXPERIMENTAL

Epirisone 50mg or placebo TID

Intervention Type DRUG

3 times a day after meals for 1 week

Epirisone 50mg TID

Group Type EXPERIMENTAL

Epirisone 50mg or placebo TID

Intervention Type DRUG

3 times a day after meals for 1 week

Placebo comparator

Group Type PLACEBO_COMPARATOR

Epirisone 50mg or placebo TID

Intervention Type DRUG

3 times a day after meals for 1 week

Interventions

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Epirisone 50mg or placebo TID

3 times a day after meals for 1 week

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Subjects who have ability to comprehend the contents of study and before participating in trial and have willingness to sign of informed consent in writing
* 20≤ age ≤60
* A patient has symptom of acute low back pain
* 4≤ VAS

Exclusion Criteria

* Subjects who cannot prohibit anti-inflammatory drug, painkiller or muscle relaxants during clinical trial
* Chronic rheumatoid arthritis patients
* Patients having a medical history of hypersensitivity to Eperisone Hydrochloride
* Subject having a hereditary problem such as galactose intolerance, Lapp lactase deficiency, or glucose galatose malabsorption
* Participation in other studies before 60 days of first dosing
* Female patients having positive pregnancy test, lactating women,planning pregnancy during clinical trial
* Inadequate subject for the clinical trial by the investigator's decision
Minimum Eligible Age

20 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hanmi Pharmaceutical Company Limited

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Hak-Sun Kim, M.D.

Role: PRINCIPAL_INVESTIGATOR

Gangnam Severance Hospital

Locations

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Hallym University Sacred Heart Hospital

Anyang, , South Korea

Site Status

CHA Bundang Medical Center

Seoul, , South Korea

Site Status

Kyung Hee University Hospital

Seoul, , South Korea

Site Status

Medical college of Yonsei University, Gangnam Severance Hospital

Seoul, , South Korea

Site Status

Severance Hospital

Seoul, , South Korea

Site Status

Countries

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South Korea

Other Identifiers

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HM-EPAC-201

Identifier Type: -

Identifier Source: org_study_id