Antimicrobial Prophylaxis in Thyroid and Parathyroid Surgery
NCT ID: NCT01805856
Last Updated: 2013-03-06
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
2164 participants
INTERVENTIONAL
2010-11-30
2012-05-31
Brief Summary
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Detailed Description
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Exclusion criteria
* Patients who did not agree to attend the randomized control study.
* Patients who received the operation including mediastinum with sternotomy.
* Patients who received the operation including additional resection of trachea, esophagus and larynx.
* Patients who received the re-operation for post-operative bleedings.
* Patients who had known allergy to cephem or penicillin.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
QUADRUPLE
Study Groups
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Group A (intervention PIPC)
Patients in group A (intervention PIPC) were given AMP of 2g PIPC intravenously just after intubation. If the operation time was longer than 3 hours, additional infusion of same dose PIPC was done. After coming back to the patients' own room, one more infusion of same dose of same drug was done.
PIPC piperacillin sodium
Group B (intervention CEZ)
Patients in Group B (intervention CEZ) were given AMP of 1g CEZ intravenously just after intubation. If the operation time was longer than 3 hours, additional infusion of same dose CEZ was done. After coming back to the patients' own room, one more infusion of same dose of same drug was done.
CEZ, cefazolin sodium
Group C (without AMP)
Patients in Group C underwent surgery without any AMP.
No interventions assigned to this group
Interventions
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PIPC piperacillin sodium
CEZ, cefazolin sodium
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Patients who received the operation including mediastinum with sternotomy.
* Patients who received the operation including additional resection of trachea, esophagus and larynx.
* Patients who received the re-operation for post-operative bleedings.
* Patients who had known allergy to cephem or penicillin.
10 Years
90 Years
ALL
No
Sponsors
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Ito Hospital
OTHER
Responsible Party
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Principal Investigators
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Takashi Uruno, MD
Role: PRINCIPAL_INVESTIGATOR
Ito Hospital
Locations
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Ito Hospital
Tokyo, , Japan
Countries
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Other Identifiers
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Ito-RCT1
Identifier Type: -
Identifier Source: org_study_id
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