Effect of Intravenous Magnesium on Postoperative Sore Throat After Thyroidectomy

NCT ID: NCT02826746

Last Updated: 2019-04-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-07-31

Study Completion Date

2019-03-31

Brief Summary

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The primary purpose of this study is to investigate the effect of intravenous magnesium on postoperative throat pain after thyroidectomy.

The secondary purpose of this study is to investigate the effect of intravenous magnesium on total dose of fentanyl in recovery room after thyroidectomy.

Detailed Description

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Conditions

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Thyroid Neoplasms

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Magnesium group

intravenous administration of Magnesium Sulfate

Group Type EXPERIMENTAL

Magnesium Sulfate

Intervention Type DRUG

adminstration of intravenous magnesium as bolus of 50 mg/kg, followed by continuous infusion at rate of 10 mg/kg/h

Control group

intravenous administration of normal saline

Group Type PLACEBO_COMPARATOR

Normal saline

Intervention Type DRUG

the same bolus and infusion volumes of normal saline

Interventions

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Magnesium Sulfate

adminstration of intravenous magnesium as bolus of 50 mg/kg, followed by continuous infusion at rate of 10 mg/kg/h

Intervention Type DRUG

Normal saline

the same bolus and infusion volumes of normal saline

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Thyroidectomy

Exclusion Criteria

* Allergy to magnesium
* Chronic pain
* Chronic opioid use
* Chronic NSAID use
* Renal dysfunction
* Liver dysfunction
* Cardiac arrythmia
* Seizure
Minimum Eligible Age

20 Years

Maximum Eligible Age

85 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Ajou University School of Medicine

OTHER

Sponsor Role lead

Responsible Party

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Ji Eun Kim

Assistant professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine

Suwon, Seoum, South Korea

Site Status

Countries

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South Korea

Other Identifiers

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AJIRB-MED-CT4-16-089

Identifier Type: -

Identifier Source: org_study_id

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