Cataract Surgery With Intracameral Triamcinolone in Infants

NCT ID: NCT01800708

Last Updated: 2013-08-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-01-31

Brief Summary

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The aim of the present study is to investigate the outcomes of congenital cataract surgery when injecting intraoperative intracameral triamcinolone versus the postoperative use of oral prednisolone.

This is a prospective, randomized clinical trial. Sixty children will be submitted to congenital cataract surgery younger than 2 years of age. They will be randomly divided in two groups. The study group will receive an intraoperative intracameral triamcinolone acetonide injection. The control group will receive prednisolone syrup postoperatively. The surgical outcomes will be assessed after one year.

Detailed Description

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Conditions

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Cataract

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Triamcinolone acetonide

The study group will receive an intraoperative intracameral injection of triamcinolone acetonide

Group Type ACTIVE_COMPARATOR

Triamcinolone acetonide

Intervention Type DRUG

Prednisolone syrup

The control group will receive prednisolone syrup postoperatively

Group Type ACTIVE_COMPARATOR

Prednisolone syrup

Intervention Type DRUG

Interventions

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Triamcinolone acetonide

Intervention Type DRUG

Prednisolone syrup

Intervention Type DRUG

Other Intervention Names

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Triancinolona Ophthalmos

Eligibility Criteria

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Inclusion Criteria

* Patients younger than 2 years of age
* Unilateral or bilateral congenital cataracts compromising the red reflex

Exclusion Criteria

* Corneal opacity
* Glaucoma
* Aniridia
* Subluxated cataract
* Traumatic cataract
* Complex microphthalmia
* Persistant hyperplastic primary vitreous
* Retinal detachment
* Patients with intraoperative complications, such as IOL implanted in the sulcus
Minimum Eligible Age

6 Weeks

Maximum Eligible Age

2 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Fundação Altino Ventura

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Marcelo Ventura, MD

Role: PRINCIPAL_INVESTIGATOR

Fundação Altino Ventura

Locations

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Altino Ventura Foundation

Recife, Pernambuco, Brazil

Site Status

Countries

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Brazil

Other Identifiers

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1

Identifier Type: -

Identifier Source: org_study_id