Does Cold Provocation Increase Brown Adipose Tissue Volume?

NCT ID: NCT01797328

Last Updated: 2017-04-25

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

28 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-02-28

Study Completion Date

2015-06-30

Brief Summary

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About 28 healthy subjects are randomized to 1 hour/day of coldprovocation or to the best of ability to avoid feeling cold, for 6 weeks. Basal metabolic rate and magnetic resonance (for determination of brown adipose tissue volume) imaging are performed before and after the study.

Detailed Description

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Conditions

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Brown Adipose Tissue, Human

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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cold provocation

cold arm

Group Type ACTIVE_COMPARATOR

cold arm

Intervention Type PROCEDURE

1 hour/day of cold provocation of such an extent that it is unpleasant but does not cause shivering

to avoid feeling cold

warm arm

Group Type ACTIVE_COMPARATOR

warm arm

Intervention Type PROCEDURE

To the best of ability avoid feeling cold during 6 weeks

Interventions

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cold arm

1 hour/day of cold provocation of such an extent that it is unpleasant but does not cause shivering

Intervention Type PROCEDURE

warm arm

To the best of ability avoid feeling cold during 6 weeks

Intervention Type PROCEDURE

Eligibility Criteria

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Exclusion Criteria

\-
Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University Hospital, Linkoeping

OTHER

Sponsor Role lead

Responsible Party

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Fredrik H Nystrom

Professor, MD, Head of internal medicine

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Faculty of Health Science, Linköping

Linköping, , Sweden

Site Status

Countries

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Sweden

Other Identifiers

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Dnr2013/41-32

Identifier Type: OTHER

Identifier Source: secondary_id

Nystrom_koldstudie

Identifier Type: -

Identifier Source: org_study_id

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