The Nuvigil and Provigil Pregnancy Registry

NCT ID: NCT01792583

Last Updated: 2024-02-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Total Enrollment

191 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-06-30

Study Completion Date

2023-11-30

Brief Summary

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The primary objective of the Nuvigil/Provigil Pregnancy Registry is to characterize the pregnancy and fetal outcomes associated with Nuvigil and Provigil exposure during pregnancy.

Detailed Description

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Both the prospective and the retrospective data are captured.

Conditions

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Narcolepsy Obstructive Sleep Apnea Shift Work Sleep Disorder

Study Design

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Observational Model Type

COHORT

Study Time Perspective

OTHER

Study Groups

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Prospective Cohort

Prospective is defined per protocol: prospective data of pregnancy exposure are data acquired prior to the knowledge of the pregnancy outcome or prior to the detection of a congenital malformation at prenatal examination (e.g. fetal ultrasound, serum markers).

Modafinil/armodafinil

Intervention Type DRUG

Retrospective Cohort

Retrospective is defined per protocol: retrospective data of pregnancy exposure are data acquired after the outcome of the pregnancy is known or after the detection of a congenital malformation on prenatal examination.

Modafinil/armodafinil

Intervention Type DRUG

Interventions

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Modafinil/armodafinil

Intervention Type DRUG

Other Intervention Names

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Provigil Nuvigil

Eligibility Criteria

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Inclusion Criteria

* Reported exposure to brand or generic formulations of Nuvigil (armodafinil) and/or Provigil (modafinil) within 6 weeks prior to becoming pregnant, or during pregnancy
* Patients who provide oral or written informed consent.
* Infant up to 1 year of age born to a female with maternal exposure to armodafinil and/or modafinil within 6 weeks prior to becoming pregnant or during pregnancy.
* Able and willing to provide healthcare professional and secondary contact information, and for the patient herself to be contacted periodically by Registry staff.

Exclusion Criteria

* Patients who refuse to provide oral or written informed consent.
* Patients not exposed to armodafinil or modafinil within 6 weeks prior to becoming pregnant or during pregnancy.
* Infants whose mother was not exposed to armodafinil or modafinil within 6 weeks prior to becoming pregnant or during pregnancy.
Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Cephalon, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Teva Pregnancy Registry

West Chester, Pennsylvania, United States

Site Status

Countries

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United States

Related Links

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Other Identifiers

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C10953/9022

Identifier Type: -

Identifier Source: org_study_id

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