Use of Positive Pressure in Morbidly Obese Patients Undergoing Reduction Stomach Surgery

NCT ID: NCT01786681

Last Updated: 2013-02-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-08-31

Study Completion Date

2011-12-31

Brief Summary

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The aim of this study was to investigate the effects of using positive pressure in the preoperative, intraoperative and postoperative morbidly obese individuals undergoing gastroplasty.

It is believed that the application of these devices before, during or after surgery can help to improve the lungs and reduce pulmonary complications after surgery to reduce the stomach.

Detailed Description

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The aim of this study was to investigate the effects of using positive pressure in the preoperative, intraoperative and postoperative morbidly obese individuals undergoing Roux-en-Y gastric bypass with regard to: lung volumes and capacities, the prevalence of atelectasis, duration of surgery and diaphragmatic mobility.

Individuals with BMI between 40 and 55 kg/m2, aged between 25 and 55 years, were submitted to Roux-en-Y type gastric bypass by laparotomy. Patients showing a normal preoperative pulmonary function test were included, but those with hemodynamic instability, a hospital stay longer than three days or the presence of postoperative complications were excluded.

The volunteers were divided into four different groups:

Gpre: subjects treated with positive pressure in the BiPAP mode (Bi-Level Positive Airway Pressure) for one hour before surgery; Gpos: individuals treated with positive airway pressure (BiPAP) for one hour after surgery; Gpeep: individuals treated with 10 cm H2O of PEEP (Positive End Expiratory Pressure) during the surgical procedure.

Gcont: individuals treated with conventional physiotherapy (CP) according to the routine service of physiotherapy of the hospital, including the techniques of pulmonary re-expansion, breathing exercises (deep breaths or fractional), the use of incentive spirometry (Respiron®), bronchial hygiene resources if necessary (Flutter® and cough active or assisted) and assisted ambulation. It should be noted that the physiotherapist was blinded to the individual's participation in the groups, and all patients received conventional physiotherapy, independent of the group in which they were included.

The respiratory evaluation (preoperative and second postoperative days) consisted of collecting the anthropometric data, a pulmonary function test and a chest radiography (inspired and expired).

Conditions

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Pulmonary Atelectasis Respiratory Tract Diseases Pathological Conditions, Signs and Symptoms

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

FACTORIAL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Investigators Outcome Assessors

Study Groups

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Positive pressure before surgery

Subjects treated with positive pressure in the BiPAP mode (Bi-Level Positive Airway Pressure) for one hour before bariatric surgery.

Group Type EXPERIMENTAL

Positive pressure

Intervention Type PROCEDURE

Positive pressure during the surgery

Individuals treated with 10 cm H2O of PEEP (Positive End Expiratory Pressure) during the surgical procedure.

Group Type EXPERIMENTAL

Positive pressure

Intervention Type PROCEDURE

Positive pressure after surgery

Subjects treated with positive pressure in the BiPAP mode (Bi-Level Positive Airway Pressure) for one hour after bariatric surgery.

Group Type EXPERIMENTAL

Positive pressure

Intervention Type PROCEDURE

Control

Individuals treated with conventional physiotherapy according to the routine service of physiotherapy of the hospital.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Positive pressure

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* BMI between 40 and 55 kg/m2
* Aged between 25 and 55 years
* Submitted to Roux-en-Y type gastric bypass by laparotomy
* Normal preoperative pulmonary function test

Exclusion Criteria

* Hemodynamic instability
* Hospital stay longer than three days
* Presence of postoperative complications
Minimum Eligible Age

25 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.

OTHER_GOV

Sponsor Role collaborator

Universidade Metodista de Piracicaba

OTHER

Sponsor Role lead

Responsible Party

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Eli Maria Pazzianotto Forti

PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Universidade Metodista de Piracicaba (UNIMEP)

Piracicaba, São Paulo, Brazil

Site Status

Countries

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Brazil

Other Identifiers

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Leticia2011

Identifier Type: -

Identifier Source: org_study_id

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