Probiotic Administration and Perennial Allergic Rhinitis
NCT ID: NCT01779895
Last Updated: 2014-04-09
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
64 participants
INTERVENTIONAL
2012-12-31
2013-09-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
QUADRUPLE
Study Groups
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NCC2461
probiotic blended in maltodextrin powder to be taken daily
Lactobacillus paracasei probiotic strain
Placebo
maltodextrin
Placebo
maltodextrin
Interventions
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Lactobacillus paracasei probiotic strain
Placebo
maltodextrin
Eligibility Criteria
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Inclusion Criteria
* Confirmed allergy (allergic rhinitis) to dust mite for more than 2 years, as determined by anamnesis and by a miniRQLQ of ≥ 1
* Positive Skin prick testing measure greater than 3mm wheal diameter to the dermatophagoides pteronyssinus species of house dust mite extract
* Body Mass Index 19-29
* Having obtained his/her informed consent
Exclusion Criteria
* Allergy to any food or medication
* Asthma
* Family history of congenital immunodeficiency or chronic consumption (more than one week at Screening) of immunosuppressive or anti-inflammatory treatments
* Ongoing treatment with antibiotics or undergoing allergen immunotherapy at Screening
* Consumption of probiotic and other dietary nutritional interventions
* More than 2 drinks/day alcohol consumption or use of illicit drugs
* Pregnant women
* Subjects with expected low compliance
* Blood donation in the past month or planning to donate blood until a month after the end of the study
* Currently participating or having participated in another interventional clinical trial during the last four weeks prior to the beginning the study
20 Years
65 Years
ALL
No
Sponsors
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Société des Produits Nestlé (SPN)
INDUSTRY
Responsible Party
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Principal Investigators
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Maurice Beaumont, MD
Role: PRINCIPAL_INVESTIGATOR
Nestlé Research Centre
Locations
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Metabolic Unit, Nestlé Research Centre
Lausanne, , Switzerland
Countries
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Other Identifiers
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12.18.MET
Identifier Type: -
Identifier Source: org_study_id
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