The GReek AntiPlatElet (GRAPE) Registry: A Multicenter Observational Prospective Investigation of Antiplatelet Treatment in Patients With Acute Coronary Syndrome Subjected to Percutaneous Coronary Intervention
NCT ID: NCT01774955
Last Updated: 2015-08-20
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
2047 participants
OBSERVATIONAL
2012-02-29
2014-12-31
Brief Summary
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In patients under ticagrelor or prasugrel treatment, platelet reactivity measurement with VerifyNow assay will be performed at Day 30
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Eligibility Criteria
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Inclusion Criteria
* Acute coronary syndrome moderate to high risk (TIMI risk score ≥3) subjected to PCI
* Informed consent
Exclusion Criteria
* Inability to give informed consent
* High probability of being unavailable for follow-up visits
18 Years
ALL
No
Sponsors
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Hellenic Cardiology Society
OTHER
University of Patras
OTHER
Responsible Party
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Dimitrios Alexopoulos
Professor of Cardiology
Locations
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Patras University Hospital
Pátrai, Achaia, Greece
G.Gennimatas General Hospital
Athens, Attica, Greece
University Hospital, Alexandroupolis
Alexandroupoli, , Greece
1st Department of Cardiology, Ippokration Hospital
Athens, , Greece
Alexandra Hospital, Athens, Greece
Athens, , Greece
Onassis Cardiac Surgery Center
Athens, , Greece
University Hospital, Ioannina
Ioannina, , Greece
Iraklion University Hospital, Iraklion, Greece
Irakleio, , Greece
Larissa University Hospital
Larissa, , Greece
Countries
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References
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Alexopoulos D, Vogiatzi C, Stavrou K, Vlassopoulou N, Perperis A, Pentara I, Xanthopoulou I. Diabetes mellitus and platelet reactivity in patients under prasugrel or ticagrelor treatment: an observational study. Cardiovasc Diabetol. 2015 May 30;14:68. doi: 10.1186/s12933-015-0232-1.
Alexopoulos D, Stavrou K, Koniari I, Gkizas V, Perperis A, Kontoprias K, Vogiatzi C, Bampouri T, Xanthopoulou I. Ticagrelor vs prasugrel one-month maintenance therapy: impact on platelet reactivity and bleeding events. Thromb Haemost. 2014 Sep 2;112(3):551-7. doi: 10.1160/TH14-02-0119. Epub 2014 Jul 3.
Alexopoulos D, Goudevenos JA, Xanthopoulou I, Deftereos S, Sitafidis G, Kanakakis I, Hamilos M, Parissis H, Ntalas IV, Angelidis C, Petousis S, Vavuranakis M, Hahalis G, Stefanadis C; GRAPE Investigators. Implementation of contemporary oral antiplatelet treatment guidelines in patients with acute coronary syndrome undergoing percutaneous coronary intervention: a report from the GReek AntiPlatelet rEgistry (GRAPE). Int J Cardiol. 2013 Oct 15;168(6):5329-35. doi: 10.1016/j.ijcard.2013.08.007. Epub 2013 Aug 15.
Other Identifiers
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GRAPE registry
Identifier Type: -
Identifier Source: org_study_id
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