Taste Acuity and Caloric Intake After Acute Morphine Administration
NCT ID: NCT01763697
Last Updated: 2014-05-29
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
NA
36 participants
INTERVENTIONAL
2013-03-31
2014-05-31
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Brain Effects of Opiate Agonist and Antagonist
NCT04342130
Dose Proportionality and Food Effect of Morphine Sulfate
NCT00994539
Healthy Volunteers Study to Estimate the Effects of Food on the Bioavailability of Oxycodone and Naltrexone/6- Β -Naltrexol From a Extended Release Formulation of Oxycodone With Sequestered Naltrexone
NCT01456507
Correlation Between the Analgesic Effect of Fentanyl Transdermal Patches and Nutritional Status in Cancer Pain Patients
NCT06369961
Intrathecal Morphine Microdose Method Sensory Changes
NCT03395275
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
FACTORIAL
BASIC_SCIENCE
DOUBLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Morhpine/Taste acuity
Taste acuity assessment after 1mg subcutaneous morphine injection
taste acuity assessment
Quantitative measurement of for tasting detection and recognition thresholds, magnitude of perception and hedonic response.
Recorded meal
Placebo/Taste acuity
Taste acuity assessment after subcutaneous placebo injection
taste acuity assessment
Quantitative measurement of for tasting detection and recognition thresholds, magnitude of perception and hedonic response.
Recorded meal
Morphine4/Taste acuity
Taste acuity assessment after 4mg subcutaneous morphine injection
taste acuity assessment
Quantitative measurement of for tasting detection and recognition thresholds, magnitude of perception and hedonic response.
Recorded meal
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
taste acuity assessment
Quantitative measurement of for tasting detection and recognition thresholds, magnitude of perception and hedonic response.
Recorded meal
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Ages of 18 to 65
Exclusion Criteria
* History of taste dysfunction
* Significant medical or Axis I psychiatric disorder
* Any trauma or surgical procedures to the head or neck region
* Medication or illicit drug more than 4 out of the last 30 days.
* Pregnancy
* Abnormal electrocardiogram findings
* Negative rating of greater than 40% of the foods available for consumption
18 Years
65 Years
ALL
Yes
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
National Institute on Drug Abuse (NIDA)
NIH
Johns Hopkins University
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Denis Antoine
Instructor
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Denis G Antoine, M.D.
Role: PRINCIPAL_INVESTIGATOR
Johns Hopkins University
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Johns Hopkins Bayview Medical Center
Baltimore, Maryland, United States
Countries
Review the countries where the study has at least one active or historical site.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
NA_00046407
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.