Environment Analysis Inside an Investigational Prescription Bottle

NCT ID: NCT03752411

Last Updated: 2023-11-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

96 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-12-05

Study Completion Date

2023-11-05

Brief Summary

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The purpose of the study is to test a research prescription bottle that will monitor the physical environment inside the bottle.

Detailed Description

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The purpose of the study is to test a research prescription bottle that will monitor the physical environment inside the bottle. The participant will be asked to keep the medication in the bottle and to remove each pill immediately before taking it.

The participant will not store medications in pill organizers, other pill bottles, pockets, purses, etc. The participant will keep a record of when the participant removes a pill from the bottle and takes it. Certain aspects of this study will be withheld from the participant to preserve the integrity of the study. This information will be revealed at the conclusion of the study.

Conditions

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Chronic Pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

DOUBLE

Participants Caregivers

Study Groups

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Research Bottle

This group will have medication dispensed in a research bottle.

Group Type EXPERIMENTAL

Research Bottle

Intervention Type OTHER

The purpose of the study is to test a research prescription bottle that will monitor the physical environment inside the bottle.

Regular prescription Bottle

This group will have medication dispensed in a regular prescription bottle

Group Type PLACEBO_COMPARATOR

Regular prescription Bottle

Intervention Type OTHER

This will test if the research bottle changes behavior relative to the research bottle

Interventions

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Research Bottle

The purpose of the study is to test a research prescription bottle that will monitor the physical environment inside the bottle.

Intervention Type OTHER

Regular prescription Bottle

This will test if the research bottle changes behavior relative to the research bottle

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* chronic pain \> 3 months duration
* major source of pain is due to low back pain diagnosis
* prescribed only one type of opioid: hydrocodone 10mg/325 mg acetaminophen
* Last urine drug study was done between 6-12 months ago
* will have a return to clinic visit in 3 months

Exclusion Criteria

* concurrent use of other opioids
* use of intrathecal device
* use of spinal cord stimulator
* presence of pain due to cancer, chemotherapy, radiation treatment and/or cancer related surgery
* dementia
* illiteracy
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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The University of Texas Medical Branch, Galveston

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Denise Wilkes, MD-PhD

Role: STUDY_DIRECTOR

University of Texas

Locations

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University of Texas Medical Branch

Galveston, Texas, United States

Site Status

Countries

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United States

References

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Robinson-Papp J, George MC, Wongmek A, Nmashie A, Merlin JS, Ali Y, Epstein L, Green M, Serban S, Sheth P, Simpson DM. The Quantitative Analgesic Questionnaire: A Tool to Capture Patient-Reported Chronic Pain Medication Use. J Pain Symptom Manage. 2015 Sep;50(3):381-6. doi: 10.1016/j.jpainsymman.2015.03.013. Epub 2015 Apr 23.

Reference Type BACKGROUND
PMID: 25912277 (View on PubMed)

Houghton DC, Merritt CR, Miller SN, Mitchell JM, Parker D, Hommel JD, Cunningham KA, Wilkes DM. Electronic Real-Time Monitoring Reveals Limited Adherence to Long-Term Opioid Prescriptions in Pain Patients. J Pain Res. 2024 May 21;17:1815-1827. doi: 10.2147/JPR.S436898. eCollection 2024.

Reference Type DERIVED
PMID: 38799276 (View on PubMed)

Other Identifiers

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18-0022

Identifier Type: -

Identifier Source: org_study_id