Comparing the Effect of TAP-catheter and Epidural Catheter on Postoperative Pain After Open Gynecologic Surgery
NCT ID: NCT01760174
Last Updated: 2015-05-12
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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WITHDRAWN
NA
INTERVENTIONAL
2016-01-31
2017-02-28
Brief Summary
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Detailed Description
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The investigators record pain-score and consumption of opioids in the first 24 hours postoperatively as well as thermoanalgesia at dermatome-levels th10-th12.
The investigators assume that the effect on postoperative pain after open gynecologic surgery is equal in the two groups.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
QUADRUPLE
Study Groups
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Bupivacain-infusion in epidural catheter
Bupivacain-infusion in epidural catheter and intermittent isotonic potassium chloride bolus in transversus abdominis plane catheter.
Bupivacain-infusion in epidural catheter
Isotonic potassium chloride, 10-25 ml in each transversus abdominis catheter, depending on patient weight. Bolus is given every 6 hours, the first bolus is given just after induction of general anesthesia and the last bolus after 24 hours.
In the epidural catheter a bolus of 8 ml bupivacaine 2,5 mg/ml is given and an infusion of isotonic potassium chloride, 4-7 ml/t depending on patient height is started and runs for the first 24 hours
Ropivacaine bolus in transversus abdominis plane catheter
Intermittent ropivacaine bolus in bilateral transversus abdominis plane catheter and isotonic potassium chloride infusion in epidural catheter.
Ropivacaine bolus in transversus abdominis plane catheter
Ropivacaine 7,5 mg/ml, 10-25 ml in each catheter, depending on patient weight, the total dose of ropivacaine is kept less than 3 mg/kg for every bolus. Bolus is given every 6 hours, the first bolus is given just after induction of general anesthesia and the last bolus after 24 hours.
In the epidural catheter a bolus of 8 ml isotonic potassium chloride is given and an infusion of isotonic potassium chloride, 4-7 ml/t depending on patient height is started and runs for the first 24 hours.
Interventions
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Ropivacaine bolus in transversus abdominis plane catheter
Ropivacaine 7,5 mg/ml, 10-25 ml in each catheter, depending on patient weight, the total dose of ropivacaine is kept less than 3 mg/kg for every bolus. Bolus is given every 6 hours, the first bolus is given just after induction of general anesthesia and the last bolus after 24 hours.
In the epidural catheter a bolus of 8 ml isotonic potassium chloride is given and an infusion of isotonic potassium chloride, 4-7 ml/t depending on patient height is started and runs for the first 24 hours.
Bupivacain-infusion in epidural catheter
Isotonic potassium chloride, 10-25 ml in each transversus abdominis catheter, depending on patient weight. Bolus is given every 6 hours, the first bolus is given just after induction of general anesthesia and the last bolus after 24 hours.
In the epidural catheter a bolus of 8 ml bupivacaine 2,5 mg/ml is given and an infusion of isotonic potassium chloride, 4-7 ml/t depending on patient height is started and runs for the first 24 hours
Eligibility Criteria
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Inclusion Criteria
* acceptance to participate
Exclusion Criteria
* daily use of strong opioids
18 Years
ALL
No
Sponsors
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Aarhus University Hospital
OTHER
Aalborg University Hospital
OTHER
Responsible Party
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Nils Bjerregaard
Consultant Anesthetist
Principal Investigators
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Nils F Bjerregaard, M.D.
Role: PRINCIPAL_INVESTIGATOR
Aalborg University Hospital
Bodil S Rasmussen, M.D. + PhD
Role: STUDY_DIRECTOR
Aalborg Sygehus
Lone Nikolajsen, M.D, PhD
Role: STUDY_CHAIR
Aarhus University Hospital
Thomas F Bendtsen, MD, PhD
Role: STUDY_CHAIR
Aarhus University Hospital
Locations
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Aalborg Hospital
Aalborg, Region Nord, Denmark
Countries
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Other Identifiers
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N-20120041
Identifier Type: -
Identifier Source: org_study_id
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