Mommy-Baby Treatment for Perinatal Depression

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

42 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-11-30

Study Completion Date

2017-01-31

Brief Summary

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Perinatal depression is a major public health problem, affecting 15% of women during pregnancy through the postpartum period, with adverse consequences for the mother, the fetus, the infant, and the family. Despite increasing evidence of the importance of this critical risk interval, little research has investigated the effects of depression treatment during pregnancy on infant outcomes. The purpose of this study is to test the feasibility, acceptability, and effectiveness of a new intervention, Interpersonal psychotherapy for the mother-infant dyad (IPT-Dyad). This intervention begins during pregnancy and continues with the mother and infant until one year postpartum. The investigators hypothesize that IPT-Dyad will be better than treatment as usual in reducing depressive symptoms, improving psychosocial functioning,increasing parenting self-efficacy, improving infant emotional development, and enhancing mother-infant relationship quality.

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Detailed Description

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Conditions

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Depressive Disorder, Major Postpartum Depression

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Dyadic Interpersonal Psychotherapy

Brief Interpersonal Psychotherapy during pregnancy followed by dyadic mother-infant psychotherapy for one year postpartum

Group Type EXPERIMENTAL

Dyadic Interpersonal Psychotherapy

Intervention Type BEHAVIORAL

This intervention consists of a brief psychotherapeutic intervention, Interpersonal Psychotherapy, during pregnancy. Interpersonal Psychotherapy focuses on improving social relationships and interpersonal communication to improve mood. The postpartum phase also utilizes developmentally appropriate strategies to improve the mother-infant relationship.

Enhanced Treatment as Usual

Personalized referral to community resources for depression treatment

Group Type ACTIVE_COMPARATOR

Enhanced Treatment as Usual

Intervention Type OTHER

This intervention consists of personalized referrals to specialty mental health providers, spiritual counselors, or other needed social services. It includes some non-specific supportive techniques delivered primarily via telephone.

Interventions

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Dyadic Interpersonal Psychotherapy

This intervention consists of a brief psychotherapeutic intervention, Interpersonal Psychotherapy, during pregnancy. Interpersonal Psychotherapy focuses on improving social relationships and interpersonal communication to improve mood. The postpartum phase also utilizes developmentally appropriate strategies to improve the mother-infant relationship.

Intervention Type BEHAVIORAL

Enhanced Treatment as Usual

This intervention consists of personalized referrals to specialty mental health providers, spiritual counselors, or other needed social services. It includes some non-specific supportive techniques delivered primarily via telephone.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Pregnant women
* 18 years and older
* between 12 and 30 weeks gestation
* Score greater than or equal to 13 on Edinburgh Depression Scale
* Structured Clinical Interview (SCID-IV) diagnosis of Major Depressive Disorder, dysthymia, or Depressive Disorder, Not otherwise Specified
* English Speaking

Exclusion Criteria

* Substance abuse or dependence in past 3 months
* Active suicidal or homicidal ideation
* Bipolar disorder, psychotic disorder
* unstable medical condition or other medical/obstetrical complication
* Evidence of severe intimate partner violence
* Ongoing psychosocial or pharmacotherapy for depression

Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No