Quality of Life After Esophagectomy for Cancer - Step 1

NCT ID: NCT01738620

Last Updated: 2017-04-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

74 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-01-31

Study Completion Date

2016-02-29

Brief Summary

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Background: A recent systematic review showed that patients undergoing esophagectomy for cancer had scores of physical function, vitality and performance of health in general significantly lower than those obtained from the reference population. The analysis of the quality of life at six months follow-up showed that the total score and physical function were better before surgery and symptoms-based scales indicated that the fatigue, dyspnoea and diarrhea were worse six months after esophagectomy. The objective of this study is therefore to assess the impact of esophageal resections for cancer on the quality of life of patients and to improve it through simple interventions of post operative care.

The study is divided into two steps.

This is step 1.

Patients will be randomized into four groups receiving respectively: psychological counseling for support plus appropriate measures to reduce sleep-wake rhythm disorders during ICU stay; psychological counseling alone; appropriate measures to reduce sleep-wake rhythm disorders during ICU stay alone; or standard care. The primary end point are the items SL (sleep disorder) and QL2 of the QLQ C30, and the secondary end point is the score of the PSQI.

Detailed Description

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Conditions

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Esophageal Cancer Sleep Disturbance Quality of Life

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Investigators Outcome Assessors

Study Groups

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psychological counseling+prevention of sleep disorders in ICU

patients will receive both psychological counseling and interventions to prevent sleep disorders during their ICU stay

Group Type EXPERIMENTAL

psychological counseling

Intervention Type BEHAVIORAL

prevention of sleep disorders in ICU

Intervention Type BEHAVIORAL

psychological counseling

patients will receive psychological counseling

Group Type EXPERIMENTAL

psychological counseling

Intervention Type BEHAVIORAL

prevention of sleep disorders in ICU

interventions to prevent sleep disorders during their ICU stay

Group Type EXPERIMENTAL

prevention of sleep disorders in ICU

Intervention Type BEHAVIORAL

standard care

patients will receive standard care

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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psychological counseling

Intervention Type BEHAVIORAL

prevention of sleep disorders in ICU

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* age above 18 years old
* scheduled for esophagectomy for cancer

Exclusion Criteria

* age below 18 years old
* incapability to autonomously fill in questionnaires
* primary language not italian
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Fondazione Guido Berlucchi

OTHER

Sponsor Role collaborator

Istituto Oncologico Veneto IRCCS

OTHER

Sponsor Role collaborator

University of Padova

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Carlo Castoro, MD

Role: PRINCIPAL_INVESTIGATOR

Istituto Oncologico Veneto (IOV-IRCCS)

Locations

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Istituto Oncologico Veneto (IOV-IRCCS)

Padua, Padova, Italy

Site Status

Countries

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Italy

References

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Geense WW, van den Boogaard M, van der Hoeven JG, Vermeulen H, Hannink G, Zegers M. Nonpharmacologic Interventions to Prevent or Mitigate Adverse Long-Term Outcomes Among ICU Survivors: A Systematic Review and Meta-Analysis. Crit Care Med. 2019 Nov;47(11):1607-1618. doi: 10.1097/CCM.0000000000003974.

Reference Type DERIVED
PMID: 31464769 (View on PubMed)

Scarpa M, Pinto E, Saraceni E, Cavallin F, Parotto M, Alfieri R, Nardi MT, Marchi MR, Cagol M, Castoro C; QOLEC Group. Randomized clinical trial of psychological support and sleep adjuvant measures for postoperative sleep disturbance in patients undergoing oesophagectomy. Br J Surg. 2017 Sep;104(10):1307-1314. doi: 10.1002/bjs.10609. Epub 2017 Jul 14.

Reference Type DERIVED
PMID: 28707741 (View on PubMed)

Other Identifiers

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QOLEC1 - step 1

Identifier Type: -

Identifier Source: org_study_id

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