Clinical Trial of Motilitone on Gastric Motor Function in Healthy Volunteers

NCT ID: NCT01719575

Last Updated: 2013-08-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-03-31

Brief Summary

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The purpose of this study is to compare the effects of Motilitone and placebo on gastric volumes, gastric emptying, small bowel transit and colon transit in female and male healthy volunteers.

Detailed Description

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Conditions

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Healthy Female and Male

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Motilitone

take motilitone 30mg three times daily for the first week After 7 day wash-out period, take placebo three times daily for the second week

Group Type OTHER

Motilitone

Intervention Type DRUG

Placebo

take placebo three times daily for the first week After 7 day wash-out period, take motilitone 30mg three times daily for the second week

Group Type OTHER

Placebo

Intervention Type DRUG

Interventions

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Motilitone

Intervention Type DRUG

Placebo

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* no gastrointestinal symptoms
* no organic lesion such as gastrointestinal malignancies, erosive esophagitis, reflux esophagitis, erosive gastroduodenitis, gastric or duodenal ulceration after having normal upper abdominal endoscopy
* written informed consent

Exclusion Criteria

* pregnant, breast-feeding female,those of childbearing age who were not using an approved method of contraception
* history of abdominal surgery that may influence gastrointestinal motility
* gastrointestinal hemorrhage, mechanical ileus, enterobrosis
* irritable bowel syndrome, inflammatory bowel disease
* severe disturbance of liver, kidney, heart,lung,blood and endocrine
* psychoneurosis, alcoholism, drug dependence
* medications that may alter evaluation of Motilitone including antibiotics,corticosteroids, NSAID within 1 month, prokinetics, H2 blocker, PPI, anticolines, erythromycin, antidepressive agents withing 2weeks
Minimum Eligible Age

20 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Dong-A Pharmaceutical Co., Ltd.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Myung-Gyu Choi, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Seul St.Mary's hospital

Locations

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the Catholic university of korea college of Medicine, Seoul St.Mary's hospital

Banpo-dong, Seocho-gu, Seoul, South Korea

Site Status

Countries

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South Korea

Other Identifiers

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DA9701_GA_IV

Identifier Type: -

Identifier Source: org_study_id