Rehabilitation in Multiple Sclerosis: Influence of Exercise on Development of Insulin Resistance, Muscle Power and Aerobic Capacity

NCT ID: NCT01718392

Last Updated: 2016-11-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

45 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-03-31

Study Completion Date

2013-09-30

Brief Summary

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the purpose of this study is to investigate the development of insulin resistance in multiple sclerosis patients + explaining the effects of a combined training programme on insulin resistance, muscle power and aerobic capacity in multiple sclerosis patients

Detailed Description

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Conditions

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Multiple Sclerosis

Keywords

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combined training insulin resistance

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Training

24 weeks combined exercise programme (supervised)

Group Type EXPERIMENTAL

Training

Intervention Type BEHAVIORAL

Control

sedentary/habitual lifestyle

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Training

Intervention Type BEHAVIORAL

Other Intervention Names

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24 weeks combined exercise programma (supervised)

Eligibility Criteria

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Inclusion Criteria

* Diagnosed MS according to the McDonald criteria
* Expanded Disability Status Scale (EDSS) between 0.5 and 6
* Be able to train 5 times in 2 weeks at the University

Exclusion Criteria

* Comorbidities like cardiovascular-, respiratory-, orthopaedic or metabolic diseases (like diabetes type 2)
* Having had an relapse in a period of 3 months prior to the start of the intervention period
* Having an relapse during the intervention period
* Pregnancy and other contra indications for physical activity
* Mental disorders
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Hasselt University

OTHER

Sponsor Role lead

Responsible Party

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Bert Op't Eijnde

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Inez Wens, M.Sc.

Role: PRINCIPAL_INVESTIGATOR

Reval/Biomed, Hasselt University

Bert Op't Eijnde, Ph.D.

Role: STUDY_CHAIR

Reval/Biomed, Hasselt University

Locations

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REVAL

Diepenbeek, , Belgium

Site Status

Countries

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Belgium

Other Identifiers

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CME 2011/311

Identifier Type: -

Identifier Source: org_study_id