Safety and Efficacy of Sufentanil NanoTab for Management of Acute Pain Following Bunionectomy

NCT ID: NCT01710345

Last Updated: 2015-01-26

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

101 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-10-31

Study Completion Date

2013-02-28

Brief Summary

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This is a dose-finding study to determine if the sublingual administration of the Sufentanil NanoTab is safe and effective in the treatment of post-operative pain.

Detailed Description

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Conditions

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Acute Pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Sufentanil NanoTab 20 mcg

Sufentanil NanoTab 20 mcg as needed every 60 minutes for 12 hours

Group Type EXPERIMENTAL

Sufentanil NanoTab 20 mcg

Intervention Type DRUG

Sufentanil NanoTab 30 mcg

Sufentanil NanoTab 30 mcg as needed every 60 minutes for 12 hours

Group Type EXPERIMENTAL

Sufentanil NanoTab 30 mcg

Intervention Type DRUG

Placebo NanoTab

Placebo NanoTab as needed every 60 minutes for 12 hours

Group Type PLACEBO_COMPARATOR

Placebo NanoTab

Intervention Type DRUG

Interventions

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Sufentanil NanoTab 20 mcg

Intervention Type DRUG

Sufentanil NanoTab 30 mcg

Intervention Type DRUG

Placebo NanoTab

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* patients scheduled for bunion surgery

Exclusion Criteria

* daily opioid use
* drug or alcohol abuse
* pregnant or breastfeeding women
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Talphera, Inc

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Lotus Clinical Research

Pasadena, California, United States

Site Status

Jean Brown Research

Salt Lake City, Utah, United States

Site Status

Countries

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United States

Other Identifiers

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SAP202

Identifier Type: -

Identifier Source: org_study_id

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