Intraoperative Floppy Iris Syndrome in Korean Patients Taking α1-Adrenergic Receptor Antagonists

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

150 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-01-31

Study Completion Date

2010-03-31

Brief Summary

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Intraoperative floppy iris syndrome (IFIS) is a recently described condition observed during cataract surgery. It has been hypothesized that irreversible atrophy of the iris dilator muscle associated with α1-adrenergic receptor antagonists (α1-ARA) is responsible for IFIS. However the prevalence of IFIS in Korean population is not reported. The purpose of this study is to evaluate the prevalence and clinical manifestations of IFIS in relation to iris anatomical change in Korean patients taking α1-ARA.

Detailed Description

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Conditions

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Intraoperative Floppy Iris Syndrome

Keywords

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occurrence of

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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α1-ARA Group

All patients on α1-ARA(α1-adrenergic receptor antagonists) medication who underwent cataract surgeries.

No interventions assigned to this group

Control Group

Age and sex-matched control subjects

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* clinical diagnosis of cataract
* korean patients

Exclusion Criteria

* history of iridocyclitis, iris neovascularization, or prior iris surgery
* traumatic cataracts, zonular dialysis, or cataracts associated with ocular disease (e.g., uveitis)

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Responsibility Role SPONSOR

Other Identifiers

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2010-01-034

Identifier Type: -

Identifier Source: org_study_id