Retrobulbar Injection of Anesthesia Versus Healon 5 in the Management of Intraoperative Floppy Iris Syndrome

NCT ID: NCT00627913

Last Updated: 2017-11-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

6 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-02-29

Study Completion Date

2010-11-11

Brief Summary

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In this study, the investigators plan to compare the incidence and complications of intraoperative floppy iris syndrome (IFIS) during cataract surgery in patients taking tamsulosin (Flomax) and treated with retrobulbar injection of anesthesia, versus injection of Healon 5 viscoelastic into the anterior chamber.

Detailed Description

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Conditions

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Intraoperative Floppy Iris Syndrome

Keywords

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Floppy Iris Syndrome

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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1

Healon 5

Group Type ACTIVE_COMPARATOR

Healon 5 injection

Intervention Type PROCEDURE

Healon 5 (2.3% Sodium hyaluronate) ophthalmic viscoelastic device will be injected into the anterior chamber as needed for pupillary dilation and adequate cataract extraction with intraocular lens placement.

2

Retrobulbar Anesthetic Injection

Group Type EXPERIMENTAL

Retrobulbar anesthetic injection

Intervention Type PROCEDURE

3-4cc of anesthetic (1% lidocaine/0.75% bupivicaine) will be injected with a 25 gauge needle into the extraocular muscle cone prior to patient and microscope positioning. Cataract extraction with intraocular lens placement will then proceed in standard fashion.

Interventions

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Healon 5 injection

Healon 5 (2.3% Sodium hyaluronate) ophthalmic viscoelastic device will be injected into the anterior chamber as needed for pupillary dilation and adequate cataract extraction with intraocular lens placement.

Intervention Type PROCEDURE

Retrobulbar anesthetic injection

3-4cc of anesthetic (1% lidocaine/0.75% bupivicaine) will be injected with a 25 gauge needle into the extraocular muscle cone prior to patient and microscope positioning. Cataract extraction with intraocular lens placement will then proceed in standard fashion.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* All cataract patients taking tamsulosin

Exclusion Criteria

* Patients with any history of iridocyclitis
* Presence of iris neovascularization
* History of prior iris surgery
* Presence of traumatic cataracts
* Presence of zonular dialysis
Minimum Eligible Age

18 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Penn State University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Ahmad A Aref, M.D.

Role: PRINCIPAL_INVESTIGATOR

The Penn State Hershey Eye Center

Locations

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Penn State Hershey Eye Center

Hershey, Pennsylvania, United States

Site Status

Countries

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United States

References

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Chang DF, Osher RH, Wang L, Koch DD. Prospective multicenter evaluation of cataract surgery in patients taking tamsulosin (Flomax). Ophthalmology. 2007 May;114(5):957-64. doi: 10.1016/j.ophtha.2007.01.011.

Reference Type BACKGROUND
PMID: 17467530 (View on PubMed)

Other Identifiers

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27170

Identifier Type: -

Identifier Source: org_study_id