Difference Between Central and Peripheral Arterial Blood Oxygen Saturation With Different CPB Strategy

NCT ID: NCT01698853

Last Updated: 2012-10-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-10-31

Study Completion Date

2013-05-31

Brief Summary

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Femoro-femoral cardiopulmonary bypass with retrograde perfusion is needed for totally thoracoscopic cardiac surgery. one of the major complication of retrograde perfusion is organ hypoperfusion.

Arterial blood gas analysis can help to detect hypoperfusion or hypoxia during retrograde perfusion. However,whether the arterial oxygenation status from different parts of the body are the same in the condition of retrograde perfusion have not been studied.

The present study is aimed to determine if there is difference in the arterial oxygenation between peripheral arterial and aortic root during the period of retrograde perfusion.In addition, the impact of artificial ventilation on the difference of arterial oxygenation will also be investigated.

Detailed Description

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All patients included will be assigned into two different groups according to the surgical approach,one group is named "NP" with normal perfusion,and the other is named "RP" with retrograde perfusion.

For all the patients,we will obtain 0.5ml blood from both peripheral arterial and aortic root for blood gas analysis at some specific time points.

We will focus on the differences of arterial oxygenation between peripheral arterial and aortic root at each group.At the same time,we will analyse the impact of artificial ventilation on it.

Conditions

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Bypass Complications Disorder of Blood Gas

Study Design

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Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* age \> 18 years old
* undergoing totally thoracoscopic cardiac surgery with cardiopulmonary bypass

Exclusion Criteria

* without informed consent
* pregnancy
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Xijing Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Hailong Dong, Doctor

Role: STUDY_CHAIR

department director

Locations

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Department of Anesthesiology, Xijing Hospital

Xi'an, Shaanxi, China

Site Status

Countries

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China

Central Contacts

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Min Chen, M.D.

Role: CONTACT

Phone: 86-13991221157

Email: [email protected]

Jing Zhao, M.D.

Role: CONTACT

Phone: 86-13892810471

Email: [email protected]

Facility Contacts

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Min Chen, M.D.

Role: primary

Jing Zhao, M.D.

Role: backup

Other Identifiers

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192837

Identifier Type: -

Identifier Source: org_study_id