Diagnostic Accuracy of Serum Bilirubin in the Prediction of Perforated Appendicitis

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-05-31

Study Completion Date

2012-09-30

Brief Summary

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Hyperbilirubinemia is reported to be a positive predictor in diagnosing perforated appendicitis. Therefore we analysed the diagnostic accuracy of serum bilirubin in discriminating between perforated and simple/no appendicitis.

Methods:

All consecutive patients undergoing appendectomy for suspected appendicitis from May 2009 to August 2011 were analysed. Primary endpoint was the diagnostic accuracy of serum bilirubin levels to detect perforated appendicitis.

Detailed Description

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Conditions

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Appendicitis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* all patients undergoing appendectomy for suspected appendicitis

Exclusion Criteria

* preexisting liver disease

Minimum Eligible Age

16 Years

Maximum Eligible Age

95 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Sven Mueller

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Sven Müller, MD

Role: PRINCIPAL_INVESTIGATOR

University Hospital Tuebingen

Locations

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Departement of Visceral- and Transplant Surgery, University of Tuebingen

Tübingen, , Germany

Site Status

Countries

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Germany

References

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Muller S, Falch C, Axt S, Wilhelm P, Hein D, Konigsrainer A, Kirschniak A. Diagnostic accuracy of hyperbilirubinaemia in anticipating appendicitis and its severity. Emerg Med J. 2015 Sep;32(9):698-702. doi: 10.1136/emermed-2013-203349. Epub 2014 Dec 4.

Reference Type DERIVED

PMID: 25476715 (View on PubMed)

Other Identifiers

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APP001

Identifier Type: -

Identifier Source: org_study_id