Measurement of Natriuretic Hormone Peptides in Exacerbation of Asthma

NCT ID: NCT01690793

Last Updated: 2015-05-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-02-28

Study Completion Date

2011-02-28

Brief Summary

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The investigators hypothesize that there is a statistically significant decrease of Natriuretic Hormone Peptides (NHPs) in subjects with asthma exacerbation compared to levels following treatment of an exacerbation of asthma.

Detailed Description

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Overall Study Design

1. Measurement of Natriuretic Hormone Peptides in individuals suffering from exacerbation of asthma.
2. Measurement of Natriuretic Hormone Peptides 5-7 days after initiation of treatment of exacerbation of asthma.
3. Measurement of Natriuretic Hormone Peptides 10-14 days after initiation of treatment of exacerbation of asthma.

3 comparisons of Natriuretic Hormone Peptides levels will be made:

1. Exacerbation compared to 5-7 days after initiation of treatment
2. Exacerbation compared to 10-14 days after initiation of treatment
3. 5-7 days after initiation of treatment compared to 10-14 days after initiation of treatment.

Samples of blood will be secured in the Division of Allergy/Immunology at the University of South Florida, Joy McCann Culverhouse Airways Disease Center. All samples will be appropriately coded to maintain confidentiality. Blood specimens will be held at minus 20 degrees Celsius.

Conditions

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ASTHMA

Eligibility Criteria

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Inclusion Criteria

* Both genders, age 18-85.
* Females who are pregnant or lactating are not eligible.
* Read and comprehend English.
* Ability to give informed consent.
* Seen in the outpatient setting at one of the clinic.
* The subject must have a history of physician diagnosed asthma for at least 1 year and must have an exacerbation of asthma for entry into the study.
Minimum Eligible Age

18 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of South Florida

OTHER

Sponsor Role lead

Responsible Party

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Richard Lockey

prinicpal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Usf Asthma Allergy and Immunology Cru

Tampa, Florida, United States

Site Status

Countries

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United States

Other Identifiers

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acute asthma

Identifier Type: -

Identifier Source: org_study_id

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